BMJ 2000;320:1277 ( 6 May )

Letters

Incidence of hospital admission does not equal incidence of disease

    Conclusions drawn from data are incorrect
    Authors' reply

Conclusions drawn from data are incorrect

The first 150 words of the full text of this article appear below.

EDITOR---We are concerned about Gaist and colleagues' methods and feel that the conclusions they draw from their data are incorrect.1

The diagnosis of subarachnoid haemorrhage was validated in a sample from only one county. Is Funen County representative of Denmark, and how was it selected? Hospitals with 10 or fewer registered patients in the study period were excluded. Why was it appropriate to exclude the smaller hospitals when they may be a source of patients with particularly low predictive value for a registered diagnosis of subarachnoid haemorrhage?

The cohort of first degree relatives was overwhelmingly made up of children, and they were the only group in table 2 for whom the incidence rate ratios were significantly different from 1. The main problem with the study is one that plagues much of the literature on subarachnoid haemorrhage---it was hospital based. The strongest predictor of survival in subarachnoid haemorrhage is age. . . . [Full text of this article]


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Relevant Article

Risk of subarachnoid haemorrhage in first degree relatives of patients with subarachnoid haemorrhage: follow up study based on national registries in Denmark
David Gaist, Michael Væth, Ioannis Tsiropoulos, Kaare Christensen, Elisabeth Corder, Jørn Olsen, and Henrik Toft Sørensen
BMJ 2000 320: 141-145. [Abstract] [Full Text] [PDF]




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