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David W Bates Division of General Medicine and
Primary Care, Brigham and Women's Hospital, 75 Francis Street, Boston,
MA 02115, USA
dbates@partners.org
| The first 150 words of the full text of this article appear below. |
Data continue to show that medication errors are frequent and that adverse drug events, or injuries due to drugs, occur more often than necessary.1-4 In fact, the frequency and consequences of iatrogenic injuries seems to dwarf the frequency of other types of injuries that have received more public attention, such as aeroplane and automobile crashes.2 A recent meta-analysis reported an overall incidence of 6.7% for serious adverse drug reactions (a term that excludes events associated with errors) in hospitals.4 Between 28% and 56% of adverse drug events are preventable. 3 5-7
Though the reasons this issue has received so little attention
are complex, the reasons that medical injuries occur with some frequency are perhaps less so; medicine is more or less a cottage industry, with little standardisation and relatively few safeguards in
comparison to, say, manufacturing. In fact, most of the systems in
place in medicine were never formally designed, and this
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