BMJ 2000;320:311 ( 29 January )

Letters

Eradication of Helicobacter pylori infection in non-ulcer dyspepsia

    Commentary did not inform or update general medical community
    Author's reply

Commentary did not inform or update general medical community

The first 150 words of the full text of this article appear below.

EDITOR---Thomson's commentary on the paper by Dominici et al on familial clustering of Helicobacter pylori was presumably intended to inform and update the general medical community.1 In relation to the eradication of H pylori in non-ulcer dyspepsia he states that, "a recent prospective study strongly suggests that there is no basis for this."2 For many years, however, this topic has been keenly debated, and it continues to be so. It is therefore unfortunate that he does not mention the Medical Research Councils's dyspepsia trial from Glasgow3 or a study from Ireland.4 Both of these studies show a positive benefit of about 10% over placebo for one-off eradication treatment in non-ulcer dyspepsia. This degree of benefit is similar to that of any other chronic treatment such as proton pump inhibitors, previously studied in non-ulcer dyspepsia. Both of these studies were published before the study that Thomson quotes.2 Furthermore, the . . . [Full text of this article]
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