Children were guaranteed regular check ups in dental study

BMJ 1999;319:1432 ( 27 November )

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Children were guaranteed regular check ups in dental study

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EDITOR $---$ In the commentary on Uhari et al's trial of xylitol chewing gum in the prevention of acute otitis media White raisedthe problem of the ethical aspects of the study protocol becauseof the possible risk of caries in the control group.¹ The objectiveof the trial was to see if regular use of xylitol chewing gumfor two months would result in a reduction in the growth of Streptococcuspneumoniae causing acute otitis media, as had been the case invitro. Children in the control group used sucrose chewing gum.The result was that the occurrence of acute otitis media was reducedby 40% but not the carriage rate of S pneumoniae.

The dental healthcare system in Finland is such that a double blind, retrospective examination of the development of cariesin the children who participated in the trial was possible. Dentalrecords of each child involved . . . [Full text of this article]

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Xylitol chewing gum in prevention of acute otitis media: double blind randomised trial: M Uhari, T Kontiokari, M Koskela, and Marjo Niemela
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