Vaccines and their real or perceived adverse effects

BMJ 1999;318:1487 ( 29 May )

Letters

Vaccines and their real or perceived adverse effects

Authors' conclusions are at odds with investigators'

Studies of adverse effects of vaccination have duty to present full picture

Authors' reply

Authors' conclusions are at odds with investigators'

The first 150 words of the full text of this article appear below.

EDITOR $---$ In responding to Jefferson's editorial about vaccination and its adverse effects Classen and Classen say that presentimmunisation schedules may exacerbate the development of type1 diabetes and that early immunisation with a cocktail of vaccinesmay prevent the development of diabetes. ¹ ²

The authors cite their unpublished reanalysis of the Finnish trial of Haemophilus influenzae type b vaccine.³ Their conclusionsare at odds with the analyses and conclusions of the investigator(JT) presented at a National Institutes of Health workshop andwere published recently.⁴ The Finnish investigators' reviewof the data could not attribute the risk of type 1 diabetes inFinnish children to differences in the timing of childhood vaccinationin the vaccine trial. The incidence of type 1 diabetes in Finlandhas risen over several decades, and the risk seems to have beenalmost linear since the early 1950s. Given the disparity of conclusions,it was suggested that Classen . . . [Full text of this article]

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Public should be told that vaccines may have long term adverse effects: John Barthelow Classen and David C Classen
BMJ 1999 318: 193. [Extract] [Full Text]