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David Torgerson a National
Primary Care Research and Development Centre, Centre for Health
Economics, University of York, York YO1 5DD, b Health Economics Facility, Health
Services Management Centre, University of Birmingham, Birmingham
B15 2RT
Correspondence to D Torgerson
| The first 150 words of the full text of this article appear below. |
To make judgments about efficiency economic evaluation of health care has to compare health outcomes, however measured, with costs. Three main approaches exist to measuring outcomes: clinical end points, quality of life measures, and willingness to pay.
The simplest outcome measure to use in a trial is a clinical one, such as a reduction in the number of strokes or changes in blood pressure. Health economists use such measures to construct cost effectiveness ratios.1 For example, in a trial aimed at preventing hip fractures a cost effectiveness ratio might be cost per averted hip fracture.
Measuring outcome in terms of clinical endpoints has the disadvantage
that comparisons between different healthcare treatments are difficult.
This is only partly solved when trial endpoints include mortality.
Although estimates of cost per life gained or life year gained allow
comparisons between very different therapies, using survival as an
outcome measure for an economic evaluation