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Study has methodological flaws
| The first 150 words of the full text of this article appear below. |
EDITOR
Jacobson and Bygdeman present intriguing data suggesting that
the risk of suicide is influenced by birth trauma; they argue that this
may explain recent increases in suicide among adolescents.1 However, deficiencies in the design and
analysis of this case-control study should be addressed before the
findings are accepted or possible mechanisms are considered.
The significant findings in Jacobson and Bygdeman's paper are
confined to a subgroup of men who committed suicide using violent methods, were born and died in the catchment area of Stockholm's forensic medicine department, and had siblings whose birth records were
available. The 175 males for whom the significant associations were
found probably represent 25% of all suicides. The authors' suggestion
that the association is restricted to violent suicides might be tested
by presenting separate risk estimates for violent and non-violent
suicides. Furthermore, there is overlap in the cases included in this
analysis and those included