Inherited predisposition to hypertension confounds the effect of low birthweight

BMJ 1999;318:943 ( 3 April )

Letters

Inherited predisposition to hypertension confounds the effect of low birthweight

The first 150 words of the full text of this article appear below.

EDITOR $---$ Our study showed that the relation between lower birthweight and subsequent higher blood pressure in adulthood maybe confounded by parental blood pressure.¹ Mothers with higherblood pressure between 9 and 19 years after delivery had babieswith lower birthweight who subsequently had higher blood pressureasadults.

Taylor et al seem to refute this finding by showing that maternal blood pressure measured during pregnancy did not confoundthe relation between lower birthweight and higher blood pressurein children aged 8-11 years.² However, they have not acknowledgedthe weakness of measurement of maternal blood pressure in pregnancy.They do not cite a study showing that, although there is no relationbetween maternal blood pressure measured in the clinic duringpregnancy and subsequent birthweight of the babies, an inverserelation is present across the range of normal blood pressuresmeasured by ambulatory monitoring.³ In addition, although thereis an association between pregnancy . . . [Full text of this article]

CiteULike

Complore

Connotea

Del.icio.us Add to Digg

Digg

StumbleUpon Add to Technorati

Technorati What's this?

Relevant Article

Contribution of parental blood pressures to association between low birth weight and adult high blood pressure: cross sectional study: Brian R Walker, Alex McConnachie, Joseph P Noon, David J Webb, and Graham C M Watt
BMJ 1998 316: 834-837. [Abstract] [Full Text] [PDF]

This article has been cited by other articles:

Murray, A., Coia, J. E., Mather, H., Brown, D. J. (2005). Ciprofloxacin resistance in non-typhoidal Salmonella serotypes in Scotland, 1993-2003. J Antimicrob Chemother 56: 110-114 [Abstract] [Full text]
Luo, N., Sahin, O., Lin, J., Michel, L. O., Zhang, Q. (2003). In Vivo Selection of Campylobacter Isolates with High Levels of Fluoroquinolone Resistance Associated with gyrA Mutations and the Function of the CmeABC Efflux Pump. Antimicrob. Agents Chemother. 47: 390-394 [Abstract] [Full text]
Winokur, P. L., Brueggemann, A., DeSalvo, D. L., Hoffmann, L., Apley, M. D., Uhlenhopp, E. K., Pfaller, M. A., Doern, G. V. (2000). Animal and Human Multidrug-Resistant, Cephalosporin-Resistant Salmonella Isolates Expressing a Plasmid-Mediated CMY-2 AmpC beta -Lactamase. Antimicrob. Agents Chemother. 44: 2777-2783 [Abstract] [Full text]