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Control limits failed to account for case mix
| The first 150 words of the full text of this article appear below. |
EDITOR
We are concerned about the graphical technique described by
Poloniecki et al in their analysis of perioperative mortality rates
associated with cardiac surgery.1 Figure 2 shows three traces: observed mortality performance bracketed by control limits and
plotted against the number of successive cases performed. The
interpretation of the middle of the traces is straightforward since it
is simply a variable life adjusted display that has previously been
described and will be familiar to many cardiac surgeons in the United
Kingdom.2 The use of control limits, on the other hand, is
new. However, the usefulness and indeed the validity of these is not
clear. As the authors themselves note, their analysis does not amount
to a formal test of significance since the control limits have not been
corrected for multiple testing; this is a major deficiency. The use of
99% control limits rather than 95% control limits presumably
increases their