BMJ 1998;317:693-694 ( 12 September )

Editorials

Combined high blood pressure and glucose in type 2 diabetes: double jeopardy

British trial shows clear effects of treatment, especially blood pressure reduction

Editorial p   691 Papers pp   703 , 713 , 720

The first 150 words of the full text of this article appear below.

More than three decades ago Harry Keen pinpointed two "bad companions" to diabetes: high blood glucose concentrations and high blood pressure, both associated with microalbuminuria. The long running UK prospective diabetes study has recently extended the number of bad companions to include dyslipidaemia and smoking.1 Owing to the complexity of the disease, however, and the slow but progressive development of complications over many years, well founded intervention strategies against diabetic complications have been largely lacking in type 2 diabetes. Papers from the UK study published this week in the BMJ and the Lancet now offer clinicians some effective treatment options.

The UK prospective diabetes study started by studying the value of various strategies to achieve tight blood glucose control compared with looser control, but the researchers soon became aware that high blood pressure may be an even stronger risk factor---as we originally observed in diabetic renal disease2---and blood pressure . . . [Full text of this article]
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