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Echocardiography and rescue angioplasty are effective for high risk patients
| The first 150 words of the full text of this article appear below. |
EDITOR
Lim and Shiels state that pooled data suggest patients do not
benefit from rescue angioplasty after failed thrombolysis and that
their outcome is adversely affected when interventional techniques fail
to open the vessel affected by the infarct.1 They also
state that "vigorous clinical assessment" is required before a
patient can be classified as high risk after thrombolytic treatment to
prevent misinterpretation of signs such as hypotension and sinus
tachycardia. Both points should be addressed.
Firstly, the only large scale randomised trial comparing rescue
angioplasty with conservative treatment for failed thrombolysis found a
significant reduction in the incidence of death or severe heart failure
among patients in the rescue angioplasty group (6% v
17%, P=0.05).2 Additionally, the trial was performed
without the use of abciximab, a glycoprotein IIb/IIIa inhibitor shown
to be beneficial in high risk angioplasty without increasing the risk
of haemorrhage.3 The trial also did not incorporate