Relation between obesity from childhood to adulthood and the metabolic syndrome: population based study

BMJ 1998;317:319-320 ( 1 August )

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Relation between obesity from childhood to adulthood and the metabolic syndrome: population based study

Mauno Vanhala, general practitioner, ^a Pasi Vanhala, general practitioner, ^a Esko Kumpusalo, lecturer, ^b Pirjo Halonen, statistician, ^b Jorma Takala, professor. ^b

^a Pieksämäki District Health Centre, PO Box 65, 76101 Pieksämäki, Finland, ^b Kuopio University, Department of Public Health and General Practice, PO Box 1627, FIN-70211 Kuopio, Finland

Correspondence to: Dr M Vanhala, Community Health Centre of the City of Imatra, Virastokatu 2, 55100 Imatra, Finland Mauno.Vanhala@pp.inet.fi

The first 150 words of the full text of this article appear below.

Most researchers agree that obesity is an important modulator of the metabolic syndrome, ¹ ² which is a clustering ofcardiovascular risk factors associated with insulin resistance $---$ suchas hypertension, hypertriglyceridaemia, a low concentration ofhigh density lipoprotein cholesterol, abnormal glucose metabolism,and hyperinsulinaemia.³ Little is known, however, about theassociation between relative weight change from childhood to adulthoodand the development of metabolic syndrome in adulthood.

	Material, methods, and results

We recently published data of a population study for the metabolic syndrome, performed during 1993-4 in Pieksämäki, Finland.All subjects (n=1008) born in the years 1947, 1952, and 1957 wereexamined according to a protocol described elsewhere.⁴ Dataon both weight and height at age 7 years (the start of primaryschool) were also collected.

Altogether, 712/1008 (70.6%) subjects participated in the study. Weights and heights at age 7 were traced for 439/712 (61.7%) participants. Obesity was defined both in childhood and in adulthoodas a sex specific highest third of . . . [Full text of this article]

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