Measles, measles vaccination, and Crohn's disease

BMJ 1998;316:1745 ( 6 June )

Letters

Measles, measles vaccination, and Crohn's disease

Second immunisation has not affected incidence in England

Crohn's disease has not increased in Finland

Age specific prevalences do not suggest association with in utero exposure

Second immunisation has not affected incidence in England

The first 150 words of the full text of this article appear below.

EDITOR $---$ Metcalf concludes that the scientific evidence does not support a causal link between measles virus and Crohn's disease.¹ Though few readers of the BMJ are likely to disagree with herappraisal of the science, parental concern about the safety of the vaccine remains high fuelled by continuing media interestin this controversial topic. More worrying is the recent declinein MMR vaccine coverage² and evidence which suggests that mostpractice nurses would not give their own child a second dose ofMMR vaccine because of concerns about vaccine safety.³

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One of the claims made by the leading proponent of the hypothesis that measles vaccine causes Crohn's disease is that therehas been a "dramatic escalation" in paediatric cases in the wakeof the 1994 national measles-rubella vaccination campaign targetedat school aged children.⁴ We have monitored hospital dischargediagnoses for Crohn's disease (ICD-9 code 555 until March 1995,ICD-10 code . . . [Full text of this article]

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