BMJ 1997;315:1437-1441 (29 November)

Education and debate

They were cheap and available: prisoners as research subjects in twentieth century America

Allen M Hornblum, instructor a

a Department of Urban Studies, Temple University, Philadelphia, PA 19122-2585, USA

Correspondence to: 7100 Bustleton Ave, Philadelphia, PA 19149, USA


right arrow   Introduction

On 20 August 1947 Gerhard Rose, one of Germany's most respected physicians, stood in the prisoner's dock at the Palace of Justice in Nuremberg, Germany, awaiting his sentence for "murders, tortures, and other atrocities committed in the name of medical science." Dr Rose, the department head for tropical medicine of the Robert Koch Institute, was on trial along with 22 of his medical colleagues, for perpetrating "ghastly" and "hideous" experiments on concentration camp prisoners during the war.1

At one point in the trial when the chief prosecution witness, Dr Andrew C Ivy of the medical school of the University of Illinois, underscored the basic principle "that human experimental subjects must be volunteers," Dr Rose and his defence counsel vigorously objected, arguing that the United States was guilty of similar medical practices and giving several examples to support this contention.1


right arrow   Early experiments on prisoners in US

The Nazi doctor's first example of American complicity . . . [Full text of this article]

Summary points


right arrow   The second world war

right arrow   Postwar experimentation

right arrow   Prison experiments during the 1960s

right arrow   The end of prison experimentation

right arrow   Acknowledgements

right arrow   References

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  • Rothman, K. J (2007). Commentary: Epidemiology still ascendant. Int J Epidemiol 36: 710-711 [Full text]  
  • Lerner, B. H. (2007). Subjects or Objects? Prisoners and Human Experimentation. NEJM 356: 1806-1807 [Full text]  
  • Gostin, L. O. (2007). Biomedical Research Involving Prisoners: Ethical Values and Legal Regulation. JAMA 297: 737-740 [Full text]  
  • Gaw, A. (2006). Beyond consent: the potential for atrocity.. JRSM 99: 175-177 [Full text]  
  • Oakes, J. M. (2002). Risks and Wrongs in Social Science Research: An Evaluator's Guide to the IRB. Eval Rev 26: 443-479 [Abstract]  
  • Parker, F. R. Jr., Paine, C. J. (1999). Informed Consent and the Refusal of Medical Treatment in the Correctional Setting. J Law Med Ethics 27: 240-251  



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