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Impact of mild cognitive impairment on survival in very elderly people: cohort study

^a Section of Gerontology and Geriatrics, Department of General Internal Medicine, University Hospital Leiden, P-3-Q PO Box 9600, 2300 RC Leiden, Netherlands, ^b Clinical Epidemiology Leiden, University Hospital Leiden, ^c Department of Psychiatry, University of Utrecht, Utrecht

Correspondence to: Dr Gussekloo

	Introduction

Severe cognitive impairment is associated with increased mortality, but the impact of mild cognitive impairment on survival remains unclear.^{1 2} Although there is doubt whether a simple test such as the mini-mental state examination has sufficient discriminatory power to detect mild cognitive impairment in elderly people,³ we determined the impact of borderline scores in this particular examination on survival in very elderly people.

	Subjects, methods, and results

As part of the Leiden 85-plus study⁴ we followed a cohort of 891 subjects (641 women, 250 men) aged 85 years and over (median age 90 (range 85 -103) years) from 1986 onwards. At entry to the study the score on the mini-mental state examination (Dutch version) was assessed by a physician during a home visit. In cooperation with the local government all but . . . [Full text of this article]

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