BMJ 1996;312:1542 (15 June)

Letters

Managing HIV disease without Delta

EDITOR,--The editorial by Anthony J Pinching gives further news of the two large randomised placebo controlled trials of combination antiretroviral therapy in advanced HIV infection. Although the apparent beneficial results have been widely publicised, neither Delta nor ACTG175 have yet been published. Are physicians therefore able to make an informed decision on the best treatment for advanced HIV infection? Peer review and debate are vital in the assessment of new data, particularly when the therapeutic and financial implications are so great. The letter columns of the BMJ after the premature release of data detailing the risks of venous thrombosis in women receiving the contraceptive pill bear testament to this.

Pinching writes of "evidence based medicine in health commissioning." Surely both providers and purchasers of health care are not yet in a position to consider such combination therapy with so much missing information. Vital data are as yet unknown with regard . . . [Full text of this article]


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Relevant Article

Managing HIV disease after Delta
Anthony J Pinching
BMJ 1996 312: 521-522. [Extract] [Full Text]

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