Raised adult blood pressure linked to failure to achieve growth potential in utero

BMJ 1996;312:1479 (8 June)

Letters

Raised adult blood pressure linked to failure to achieve growth potential in utero

EDITOR,--In their study of men in Uppsala, David A Leon andcolleagues found that the highest blood pressures were in menwho had been small babies but grew to be tall adults.¹ Theyargue that these babies failed to achieve their growth potentialin utero. We replicated their analysis in three studies of menborn in England (in Hertfordshire (in 1920-30, n = 841), Preston(1935-43, n = 239), and Sheffield (1939-41, n = 170)). Theirblood pressures were measured at ages 59-70, 46-54, and 50-53respectively. Details of the methods have been published.² ³⁴

Table 1 shows the results for the men living in Hertfordshire,with the groups as defined by Leon and colleagues. As in Uppsala,the inverse relation between blood pressure and birth weightwas stronger in men who were taller than 176 cm (the medianheight in Uppsala) and the highest pressures were in men whohad . . . [Full text of this article]

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