Premature coronary deaths in Asians

BMJ 1996;312:508 (24 February)

Letters

Premature coronary deaths in Asians

EDITOR,--Sandeep Gupta and colleagues discuss ways in whichpremature coronary deaths in Asians in Britain might be avoided.¹When cooking, many people in India and Pakistan use a semisolidfat obtained by partially hydrogenating vegetable oils. Thisproduct, called vanaspathi or vegetable ghee, contains highlevels of trans-fatty acids, which adversely affect blood lipidconcentrations and are thus likely to increase the risk of coronaryheart disease.²

As part of a pilot investigation conducted at the National Instituteof Cardiovascular Diseases in Karachi to assess the feasibilityof a case-control study we collected specimens of subcutaneousfat from 48 subjects. The samples were collected by a modificationof the technique described by Beynen and Katan,³ stored at 70°C,and transported to the United States on dry ice. Fatty acidswere extracted and analysed by capillary gas chromatographywith a 100 m column. We found that the 14 subjects who used. . . [Full text of this article]

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Avoiding premature coronary deaths in Asians in Britain: Sandeep Gupta, Adam de Belder, and Liam O Hughes
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