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EDITOR,--In his editorial Iain Smith calls for research to obtain evidence of the efficacy of complementary procedures, and we agree that "the burden of proof should be no greater, or less, than for mainstream medicine."1 In the next paragraph, however, he says that randomised controlled trials "may fail to allow for the holistic effect that is central to the philosophy of most complementary therapies" and that "the beneficial effects are often so obvious, the side effects so rare and mild, and the duration of effect so variable after even a single exposure that perhaps observational studies may be enough to prove benefit." He then cites Black, who quotes defibrillation for ventricular fibrillation as an example of a treatment with an impact so large that observational data are sufficient to show it.2
We are unconvinced by this argument. In conventional medicine the mildness
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