Papers

Randomised clinical trial of medical evacuation and surgical curettage for incomplete miscarriage

^a Department of Obstetrics and Gynaecology, Kalafong Hospital, University of Pretoria, Private Bag X 396, Pretoria 0001, Republic of South Africa

Correspondence to: Dr de Jonge.

In South Africa surgical curettage under general anaesthesia is considered to be the standard management for incomplete miscarriage. It constitutes a substantial proportion of the gynaecological services rendered and therefore places an ever increasing burden on the medical resources available. Research into the safety and efficacy of outpatient surgical curettage has resulted in a cost effective procedure with minimal illness.^{1 2} Henshaw et al, however, have shown that medical management of an uncomplicated incomplete first trimester miscarriage with misoprostol, a synthetic prostaglandin analogue, had a 96% success rate and may be a suitable cost saving alternative.³ We compared medical with surgical management in terms of efficacy and morbidity.

Patients, methods, and results

We conducted a randomised clinical trial of 50 consecutive patients fulfilling the following eligibility criteria: history of amenorrhoea followed by abdominal . . . [Full text of this article]

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    StumbleUpon    Technorati    What's this?

Relevant Article

Management of miscarriage: expectant, medical, or surgical? Results of randomised controlled trial (miscarriage treatment (MIST) trial)

J Trinder, P Brocklehurst, R Porter, M Read, S Vyas, and L Smith
BMJ 2006 332: 1235-1240. [Abstract] [Full Text] [PDF]

This article has been cited by other articles:

• Trinder, J, Brocklehurst, P, Porter, R, Read, M, Vyas, S, Smith, L (2006). Management of miscarriage: expectant, medical, or surgical? Results of randomised controlled trial (miscarriage treatment (MIST) trial). BMJ 332: 1235-1240 [Abstract] [Full text]  
• Davis, A.R., Robilotto, C.M., Westhoff, C.L., Forman, S., Zhang, J., for the NICHD Management of Early Pregnancy Failur, (2004). Bleeding patterns after vaginal misoprostol for treatment of early pregnancy failure. Hum Reprod 19: 1655-1658 [Abstract] [Full text]  
• Pang, M.W., Lee, T.S., Chung, T.K.H. (2001). Incomplete miscarriage: a randomized controlled trial comparing oral with vaginal misoprostol for medical evacuation. Hum Reprod 16: 2283-2287 [Abstract] [Full text]  
• Weeks, A., Alia, G. (2001). Ultrasonography may have role in assessing spontaneous miscarriage. BMJ 323: 694-694 [Full text]  
• Wagaarachchi, P.T., Ashok, P.W., Narvekar, N., Smith, N.C., Templeton, A. (2001). Medical management of early fetal demise using a combination of mifepristone and misoprostol. Hum Reprod 16: 1849-1853 [Abstract] [Full text]  
• Ankum, W. M, Waard, M. W.-d., Bindels, P. J E (2001). Regular review: Management of spontaneous miscarriage in the first trimester: an example of putting informed shared decision making into practice. BMJ 322: 1343-1346 [Full text]  
• Demetroulis, C., Saridogan, E., Kunde, D., Naftalin, A. A. (2001). A prospective randomized control trial comparing medical and surgical treatment for early pregnancy failure. Hum Reprod 16: 365-369 [Abstract] [Full text]  
• Goldberg, A. B., Greenberg, M. B., Darney, P. D. (2001). Misoprostol and Pregnancy. NEJM 344: 38-47 [Full text]