BMJ 1995;310:1619-1620 (24 June)

Editorials

Hepatitis C and haemophilia

Coinfection with HIV is common and will demand great resources

The haemophilic community in Britain, already hit by HIV infection, is now facing the problem of chronic hepatitis C. The high incidence of hepatitis after treatment with clotting factor concentrate from a large pool was first identified by Kasper and Kipnis in 1972.1 They found that infection was more common in young patients having their first treatment. It is now known that there was virtually a 100% rate of transmission of hepatitis C virus to previously untreated patients with haemophilia until effective procedures to inactivate the virus were introduced in 1985-6.2 3 Transmission of hepatitis C occurred with plasma from NHS and commercial sources. Studies of the hepatitis C virus genotype found in British patients with haemophilia who have been treated with concentrates have shown types 1, 2, and 3, reflecting contamination from the British and North American donor pool. Type . . . [Full text of this article]


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Relevant Article

Hepatitis C and haemophilia
Peter R Foster, Ronald V Mcintosh, and Alexander J Macleod
BMJ 1995 311: 754-755. [Extract] [Full Text]

This article has been cited by other articles:

  • Booth, J C L, O'Grady, J, Neuberger, J (2001). Clinical guidelines on the management of hepatitis C. Gut 49: I1-21 [Full text]  
  • Lee, C., Sabin, C., Miners, A. (1997). High cost, low volume care: the case of haemophilia. BMJ 315: 962-963 [Full text]  
  • Foster, P. R, Mcintosh, R. V, Macleod, A. J (1995). Hepatitis C and haemophilia. BMJ 311: 754c-755 [Full text]  
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