BMJ 1994;309:1101-1102 (29 October)

Editorials

Dietary protein and progression of chronic renal disease

Healthy people rightly consider food for its culinary rather than its biochemical value. With the present state of knowledge, only broad guidelines are appropriate as to what constitutes a healthy diet. In some conditions, however, diet can be critically important to health. This imposes a considerable strain on patients and their families, and maintaining a stringent dietary regimen for a long time is notoriously difficult.

Suggestions from animal studies that restricting dietary protein might slow or abort a steady fall in the glomerular filtration rate aroused much interest in those managing potentially progressive renal disease.1,2 After these early reports several small but disciplined studies of the value of restricting protein intake in humans were published, and these were subjected to a meta-analysis reported in this journal.3 The authors concluded that the evidence strongly supported the effectiveness of low protein diets in delaying the onset of end stage renal disease, and . . . [Full text of this article]


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