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These environmental improvements, coupled with methodological criticisms of the early reports, have tended to dispel concern. A major 10 year prospective study of 11 000 women doctors in the United Kingdom, which followed them through 13 500 pregnancies till 1986, was also reassuring (R P Knill-Jones, personal communication, 1992). This study did not confirm the earlier work of the 1970s and showed no relation between hours spent
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