BMJ 1994;309:877 (1 October)

Letters

Using CD4 lymphocyte count to predict survival with HIV infection

EDITOR, - Andrew N Phillips and colleagues used the CD4 lymphocyte count to predict long term survival after HIV infection in men with haemophilia,1 but the biological variables that influence the CD4 count limit the applicability of their results to other risk groups - for example, homosexual men.

I studied 25 HIV positive patients who had been followed up for more than six years in my clinic. Eleven were homosexual men, of whom three died of AIDS and three others developed AIDS during the follow up; one patient had a low CD4 lymphocyte count (100x106/l, but the four others remained asymptomatic with counts of over 300x106/l. Nine patients had been injecting drug users: two of these died in the sixth and seventh years after diagnosis while the rest remained asymptomatic with CD4 lymphocyte counts of over 300x106/l during the six years of follow up. The five other . . . [Full text of this article]


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