BMJ 1994;309:754-755 (24 September)

Editorials

Insulin dependent diabetes mellitus: a lethal disease in the developing world

Some patients are dying for lack of insulin

Before the discovery of insulin in 1921 the diagnosis of insulin dependent diabetes mellitus was tantamount to a death sentence, with 40% or more diabetic patients dying of ketoacidosis. This changed dramatically after 1921, with ketoacidosis becoming a minor cause of death. Life expectancy increased appreciably, although not to the extent hoped for because of the emergence of nephropathy and ischaemic heart disease.

Now, with improved treatment and prevention, life expectancy is good for a patient with newly diagnosed insulin dependent diabetes mellitus. Thus someone in whom the disease was diagnosed before the age of 17 in Pittsburgh between 1950 and 1981 had an 88% chance of surviving 20 years.1 Survival now would be even better, and the results of the recent diabetic control and complications trial give hope for further improvement.2

Sadly, this is not the situation worldwide. Insulin dependent diabetes . . . [Full text of this article]


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Relevant Article

Diabetes in the developing world
J E Foster
BMJ 1994 309: 1375. [Extract] [Full Text]

This article has been cited by other articles:

  • Lakhani, Z. (1995). Diabetes in the developing world. BMJ 310: 403a-403 [Full text]  
  • Foster, J E (1994). Diabetes in the developing world. BMJ 309: 1375a-1375 [Full text]  
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