BMJ 1994;309:476 (13 August)

Letters

Falling sperm quality

EDITOR, - It has been suggested that environmental factors, possibly acting in fetal and early neonatal life, may be having long term adverse effects on the male reproductive system,1 and that this is leading to an observed deterioration in semen quality2 together with an increase in the incidence of congenital malformations of the male reproductive tract, and in the incidence of testicular cancer. Although this is currently little more than a compelling hypothesis, if true it has very profound implications for those involved in fundamental research as well as those involved in the clinical care of men with reproductive disorders. We thus read with great interest the paper by Peter Bromwich and colleagues,3 together with the associated editorial by Stephen Farrow.4

Bromwich and colleagues make much of the statistical observation, well known to workers in the field of andrology, that measures of human semen quality are seldom normally distributed, and . . . [Full text of this article]


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