BMJ 1994;308:1301-1302 (14 May)
Letters
Blood pressure and myocardial infarction Low blood pressure can be hazardous
EDITOR, - The study of Ulf Lindblad and colleagues highlights a high risk group of hypertensive patients with evidence on electrocardiography of ischaemia or left ventricular hypertrophy, or both, who experience a greater number of first myocardial infarctions (than those with normal electrocardiograms) if their diastolic blood pressure is lowered to below 95 mm Hg.1 These new data supplement the findings of the Framingham study, which showed no J curve relation between diastolic blood pressure and deaths from coronary heart disease for those without coronary heart disease or left ventricular hypertrophy. By contrast, those with either coronary heart disease or left ventricular hypertrophy showed a J point in the high 70s of diastolic blood pressure and those with combined coronary heart disease and left ventricular hypertrophy had a J point shifted to the right at pressures of 85-89 mm Hg.
Lindblad and colleagues indicate that left ventricular hypertrophy is associated . . . [Full text of this article]

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Control of blood pressure and risk of first acute myocardial infarction: Skaraborg hypertension project
- U Lindblad, L Ramstam, L Ryden, J Ranstam, S-O Isacsson, and G Berglund
BMJ 1994 308: 681-685.
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