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Published 10 February 2009, doi:10.1136/bmj.b270
Cite this as: BMJ 2009;338:b270
Gerry Richardson, senior research fellow1, Karen Bloor, senior research fellow2, John Williams, professor3, Ian Russell, director4, Dharmaraj Durai, consultant gastroenterologist5, Wai Yee Cheung, senior lecturer3, Amanda Farrin, director and principal statistician (health sciences division)6, Simon Coulton, reader in health services research7
1 Centre for Health Economics and Hull York Medical School (HYMS), University of York, York YO10 5DD, 2 Department of Health Sciences, University of York, York, 3 Centre for Health Information, Research and Evaluation, School of Medicine, Swansea University, Swansea, 4 North Wales Organisation for Randomised Trials in Health, Institute for Medical and Social Care Research, Bangor University, Gwynedd, 5 Wishaw General Hospital, Wishaw, Lanarkshire, 6 Clinical Trials Research Unit, University of Leeds, Leeds, 7 Centre for Health Services Studies, University of Kent, Canterbury, Kent
Correspondence to: G Richardson gar2{at}york.ac.uk
Design As part of a pragmatic randomised trial, the economic analysis calculated incremental cost effectiveness ratios, and generated cost effectiveness acceptability curves to address uncertainty.
Setting 23 hospitals in the United Kingdom.
Participants 67 doctors and 30 nurses, with a total of 1888 patients, from July 2002 to June 2003.
Intervention Diagnostic upper gastrointestinal endoscopy and flexible sigmoidoscopy carried out by doctors or nurses.
Main outcome measure Estimated health gains in QALYs measured with EQ-5D. Probability of cost effectiveness over a range of decision makers willingness to pay for an additional quality adjusted life year (QALY).
Results Although differences did not reach traditional levels of significance, patients in the doctor group gained 0.015 QALYs more than those in the nurse group, at an increased cost of about £56 (
59, $78) per patient. This yields an incremental cost effectiveness ratio of £3660 (
3876, $5097) per QALY. Though there is uncertainty around these results, doctors are probably more cost effective than nurses for plausible values of a QALY.
Conclusions Though upper gastrointestinal endoscopies and flexible sigmoidoscopies carried out by doctors cost slightly more than those by nurses and improved health outcomes only slightly, our analysis favours endoscopies by doctors. For plausible values of decision makers willingness to pay for an extra QALY, endoscopy delivered by nurses is unlikely to be cost effective compared with endoscopy delivered by doctors.
Trial registration International standard RCT 82765705
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