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Published 23 September 2008, doi:10.1136/bmj.a1411
Cite this as: BMJ 2008;337:a1411
Philippa Howden-Chapman, professor and director1, Nevil Pierse, statistician1, Sarah Nicholls, programme manager1, Julie Gillespie-Bennett, PhD student1, Helen Viggers, research fellow1, Malcolm Cunningham, principal physicist2, Robyn Phipps, director3, Mikael Boulic, PhD student3, Pär Fjällström, postdoctoral student3, Sarah Free, MPH student1, Ralph Chapman, associate professor and director of environmental studies4, Bob Lloyd, associate professor and director5, Kristin Wickens, senior research fellow6, David Shields, research assistant1, Michael Baker, associate professor and codirector1, Chris Cunningham, professor7, Alistair Woodward, professor and head8, Chris Bullen, associate director of clinical trials unit8, Julian Crane, professor and codirector1
1 He Kainga Oranga/Housing and Health Research Programme, University of Otago, Wellington, PO 7343, Wellington South, New Zealand,
2 BRANZ, Porirua City, New Zealand,
3 School of Engineering and Advanced Technology, Massey University, Palmerston North, New Zealand,
4 School of Geography, Environment and Earth Sciences, Victoria University, Wellington,
5 Energy Studies, Physics Department, University of Otago, Dunedin, New Zealand,
6 Wellington Asthma Research Group, University of Otago,
7 Research Centre for M
ori Health and Development, Massey University, Wellington,
8 School of Population Health, University of Auckland
Correspondence to: P Howden-Chapman philippa.howden-chapman{at}otago.ac.nz
Design Randomised controlled trial.
Setting Households in five communities in New Zealand.
Participants 409 children aged 6-12 years with doctor diagnosed asthma.
Interventions Installation of a non-polluting, more effective home heater before winter. The control group received a replacement heater at the end of the trial.
Main outcome measures The primary outcome was change in lung function (peak expiratory flow rate and forced expiratory volume in one second, FEV1). Secondary outcomes were child reported respiratory tract symptoms and daily use of preventer and reliever drugs. At the end of winter 2005 (baseline) and winter 2006 (follow-up) parents reported their childs general health, use of health services, overall respiratory health, and housing conditions. Nitrogen dioxide levels were measured monthly for four months and temperatures in the living room and childs bedroom were recorded hourly.
Results Improvements in lung function were not significant (difference in mean FEV1 130.7 ml, 95% confidence interval –20.3 to 281.7). Compared with children in the control group, however, children in the intervention group had 1.80 fewer days off school (95% confidence interval 0.11 to 3.13), 0.40 fewer visits to a doctor for asthma (0.11 to 0.62), and 0.25 fewer visits to a pharmacist for asthma (0.09 to 0.32). Children in the intervention group also had fewer reports of poor health (adjusted odds ratio 0.48, 95% confidence interval 0.31 to 0.74), less sleep disturbed by wheezing (0.55, 0.35 to 0.85), less dry cough at night (0.52, 0.32 to 0.83), and reduced scores for lower respiratory tract symptoms (0.77, 0.73 to 0.81) than children in the control group. The intervention was associated with a mean temperature rise in the living room of 1.10°C (95% confidence interval 0.54°C to 1.64°C) and in the childs bedroom of 0.57°C (0.05°C to 1.08°C). Lower levels of nitrogen dioxide were measured in the living rooms of the intervention households than in those of the control households (geometric mean 8.5 µg/m3 v 15.7 µg/m3, P<0.001). A similar effect was found in the childrens bedrooms (7.3 µg/m3 v 10.9 µg/m3, P<0.001).
Conclusion Installing non-polluting, more effective heating in the homes of children with asthma did not significantly improve lung function but did significantly reduce symptoms of asthma, days off school, healthcare utilisation, and visits to a pharmacist.
Trial registration Clinical Trials NCT00489762 [ClinicalTrials.gov] .
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