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Published 18 November 2008, doi:10.1136/bmj.a2205
Cite this as: BMJ 2008;337:a2205
Dag Tidemalm, PhD student1, Niklas Långström, associate professor2, Paul Lichtenstein, professor3, Bo Runeson, professor4
1 Department of Clinical Neuroscience, Karolinska Institutet, Division of Psychiatry, St Göran, SE-112 81 Stockholm, Sweden, 2 Centre for Violence Prevention, Karolinska Institutet, 3 Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 4 Department of Clinical Neuroscience, Karolinska Institutet
Correspondence to: D Tidemalm dag.tidemalm{at}ki.se
Design Cohort study with follow-up for 21-31 years.
Setting Swedish national register based study.
Participants 39 685 people (53% women) admitted to hospital for attempted suicide during 1973-82.
Main outcome measure Completed suicide during 1973-2003.
Results A high proportion of suicides in all diagnostic categories took place within the first year of follow-up (14-64% in men, 14-54% in women); the highest short term risk was associated with bipolar and unipolar disorder (64% in men, 42% in women) and schizophrenia (56% in men, 54% in women). The strongest psychiatric predictors of completed suicide throughout the entire follow-up were schizophrenia (adjusted hazard ratio 4.1, 95% confidence interval 3.5 to 4.8 in men, 3.5, 2.8 to 4.4 in women) and bipolar and unipolar disorder (3.5, 3.0 to 4.2 in men, 2.5, 2.1 to 3.0 in women). Increased risks were also found for other depressive disorder, anxiety disorder, alcohol misuse (women), drug misuse, and personality disorder. The highest population attributable fractions for suicide among people who had previously attempted suicide were found for other depression in women (population attributable fraction 9.3), followed by schizophrenia in men (4.6), and bipolar and unipolar disorder in women and men (4.1 and 4.0, respectively).
Conclusion Type of psychiatric disorder coexistent with a suicide attempt substantially influences overall risk and temporality for completed suicide. To reduce this risk, high risk patients need aftercare, especially during the first two years after attempted suicide among patients with schizophrenia or bipolar and unipolar disorder.
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