BMJ  2005;331:478 (3 September), doi:10.1136/bmj.38512.618681.E0 (published 26 July 2005)

Paper

Household based treatment of drinking water with flocculant-disinfectant for preventing diarrhoea in areas with turbid source water in rural western Kenya: cluster randomised controlled trial

¹ Foodborne and Diarrhoeal Diseases Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, MS A-38, Atlanta, Georgia 30333, USA, ² Centers for Disease Control and Prevention, PO Box 1578, Kisumu, Kenya, ³ Procter & Gamble Health Sciences Institute, 8700 Mason Montgomery Road, Mason, Ohio 45040, USA, ⁴ Biostatistics and Informatics Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Georgia, ⁵ Center for Vector Biology Control and Research, Kenya Medical Research Institute, PO Box 1578, Kisumu, Kenya

Objective To compare the effect on prevalence of diarrhoea and mortality of household based treatment of drinking water with flocculant-disinfectant, sodium hypochlorite, and standard practices in areas with turbid water source in Africa.

Design Cluster randomised controlled trial over 20 weeks.

Setting Family compounds, each containing several houses, in rural western Kenya.

Participants 6650 people in 605 family compounds.

Intervention Water treatment: flocculant-disinfectant, sodium hypochlorite, and usual practice (control).

Main outcome measures Prevalence of diarrhoea and all cause mortality. Escherichia coli concentration, free residual chlorine concentration, and turbidity in household drinking water as surrogates for effectiveness of water treatment.

Results In children < 2 years old, compared with those in the control compounds, the absolute difference in prevalence of diarrhoea was –25% in the flocculant-disinfectant arm (95% confidence interval –40 to –5) and –17% in the sodium hypochlorite arm (–34 to 4). In all age groups compared with control, the absolute difference in prevalence was –19% in the flocculant-disinfectant arm (–34 to –2) and –26% in the sodium hypochlorite arm (–39 to –9). There were significantly fewer deaths in the intervention compounds than in the control compounds (relative risk of death 0.58, P = 0.036). Fourteen per cent of water samples from control compounds had E coli concentrations < 1 CFU/100 ml compared with 82% in flocculant-disinfectant and 78% in sodium hypochlorite compounds. The mean turbidity of drinking water was 8 nephelometric turbidity units (NTU) in flocculant-disinfectant households, compared with 55 NTU in the two other compounds (P < 0.001).

Conclusions In areas of turbid water, flocculant-disinfectant was associated with a significant reduction in diarrhoea among children < 2 years. This health benefit, combined with a significant reduction in turbidity, suggests that the flocculant-disinfectant is well suited to areas with highly contaminated and turbid water.

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

Related Articles

Making dirty water drinkable: ...as is the drumstick tree

Arunachalam Kumar and C Jairaj Kumar
BMJ 2005 331: 781. [Extract] [Full Text]

Flocculant-disinfection gives best results in Kenya
BMJ 2005 331: 0. [Full Text]

Uncomfortable findings

Fiona Godlee
BMJ 2005 331: 0. [Extract] [Full Text] [PDF]

Clean drinking water for homes in Africa and other less developed countries

James K Tumwine
BMJ 2005 331: 468-469. [Extract] [Full Text] [PDF]

This article has been cited by other articles:

• Zwane, A. P., Kremer, M. (2007). What Works in Fighting Diarrheal Diseases in Developing Countries? A Critical Review. WORLD BANK RES OBS 0: lkm002v1-24 [Abstract] [Full text]  
• ARNOLD, B. F., COLFORD, J. M. JR (2007). TREATING WATER WITH CHLORINE AT POINT-OF-USE TO IMPROVE WATER QUALITY AND REDUCE CHILD DIARRHEA IN DEVELOPING COUNTRIES: A SYSTEMATIC REVIEW AND META-ANALYSIS. Am J Trop Med Hyg 76: 354-364 [Abstract] [Full text]  
• SHRESTHA, R. K., MARSEILLE, E., KAHN, J. G., LULE, J. R., PITTER, C., BLANDFORD, J. M., BUNNELL, R., COUTINHO, A., KIZITO, F., QUICK, R., MERMIN, J. (2006). COST-EFFECTIVENESS OF HOME-BASED CHLORINATION AND SAFE WATER STORAGE IN REDUCING DIARRHEA AMONG HIV-AFFECTED HOUSEHOLDS IN RURAL UGANDA.. Am J Trop Med Hyg 74: 884-890 [Abstract] [Full text]  
• Kumar, A., Kumar, C J. (2005). Making dirty water drinkable: ...as is the drumstick tree. BMJ 331: 781-781 [Full text]  
• Tumwine, J. K (2005). Clean drinking water for homes in Africa and other less developed countries. BMJ 331: 468-469 [Full text]  

Rapid Responses:

Read all Rapid Responses

Moringa oleifera: a non-chemical alternative water purification

Arunachalam, Kumar, et al.
bmj.com, 4 Sep 2005 [Full text]

How sustainable is disinfection of water at household level?

Adamson S. Muula
bmj.com, 14 Sep 2005 [Full text]