BMJ 2004;328:680 (20 March), doi:10.1136/bmj.328.7441.680
Primary care
Interventions for the prevention of falls in older adults: systematic review and meta-analysis of randomised clinical trials
John T Chang, clinical instructor1,
Sally C Morton, codirector2,
Laurence Z Rubenstein, professor3,
Walter A Mojica, physician reviewer2,
Margaret Maglione, policy analyst2,
Marika J Suttorp, quantitative analyst2,
Elizabeth A Roth, senior programmer analyst2,
Paul G Shekelle, professor1
1 Department of Medicine, Division of General Internal Medicine and Health Services Research, David Geffen School of Medicine, University of California at Los Angeles, CA 90095, USA,
2 Southern California Evidence-Based Practice Center, RAND Health, Santa Monica, CA 90407, USA,
3 Greater Los Angeles VA Medical Center, Sepulveda, CA 91343, USA
Correspondence to: J T Chang, Division of General Internal Medicine and Health Services Research, 911 Broxton Avenue, Los Angeles, CA 90095-1736, USA johnchang{at}mednet.ucla.edu
Objective To assess the relative effectiveness of interventions to prevent falls in older adults to either a usual care group or control group.
Design Systematic review and meta-analyses.
Data sources Medline, HealthSTAR, Embase, the Cochrane Library, other health related databases, and the reference lists from review articles and systematic reviews.
Data extraction Components of falls intervention: multifactorial falls risk assessment with management programme, exercise, environmental modifications, or education.
Results 40 trials were identified. A random effects analysis combining trials with risk ratio data showed a reduction in the risk of falling (risk ratio 0.88, 95% confidence interval 0.82 to 0.95), whereas combining trials with incidence rate data showed a reduction in the monthly rate of falling (incidence rate ratio 0.80, 0.72 to 0.88). The effect of individual components was assessed by meta-regression. A multifactorial falls risk assessment and management programme was the most effective component on risk of falling (0.82, 0.72 to 0.94, number needed to treat 11) and monthly fall rate (0.63, 0.49 to 0.83; 11.8 fewer falls in treatment group per 100 patients per month). Exercise interventions also had a beneficial effect on the risk of falling (0.86, 0.75 to 0.99, number needed to treat 16) and monthly fall rate (0.86, 0.73 to 1.01; 2.7).
Conclusions Interventions to prevent falls in older adults are effective in reducing both the risk of falling and the monthly rate of falling. The most effective intervention was a multifactorial falls risk assessment and management programme. Exercise programmes were also effective in reducing the risk of falling.

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