BMJ  2003;327:364 (16 August), doi:10.1136/bmj.327.7411.364

Paper

Sickness absence as a global measure of health: evidence from mortality in the Whitehall II prospective cohort study

Mika Kivimäki, professor1, Jenny Head, senior lecturer2, Jane E Ferrie, senior research fellow2, Martin J Shipley, senior lecturer2, Jussi Vahtera, senior researcher1, Michael G Marmot, professor2

1 Finnish Institute of Occupational Health, Topeliuksenkatu 41 aA, FIN-00250 Helsinki, Finland, 2 International Centre for Health and Society, Department of Epidemiology and Public Health, University College London Medical School, London WC1E 6BT

Correspondence to: M Kivimäki mika.kivimaki{at}ttl.fi

Objective To examine the association between sickness absence and mortality compared with associations between established health indicators and mortality.

Design Prospective cohort study. Medical examination and questionnaire survey conducted in 1985-8; sickness absence records covered the period 1985-98.

Setting 20 civil service departments in London.

Participants 6895 male and 3413 female civil servants aged 35-55 years.

Main outcome measure All cause mortality until the end of 1999.

Results After adjustment for age and grade, men and women who had more than five medically certified absences (spells > 7 days) per 10 years had a mortality 4.8 (95% confidence interval 3.3 to 6.9) and 2.7 (1.5 to 4.9) times greater than those with no such absence. Poor self rated health, presence of longstanding illness, and a measure of common clinical conditions comprising diabetes, diagnosed heart disease, abnormalities on electrocardiogram, hypertension, and respiratory illness were all associated with mortality—relative rates between 1.3 and 1.9. In a multivariate model including all the above health indicators and additional health risk factors, medically certified sickness absence remained a significant predictor of mortality. No linear association existed between self certified absence (spells 1-7 days) and mortality, but the findings suggest that a small amount of self certified absence is protective.

Conclusion Evidence linking sickness absence to mortality indicates that routinely collected sickness absence data could be used as a global measure of health differentials between employees. However, such approaches should focus on medically certified (or long term) absences rather than self certified absences.


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to StumbleUpon StumbleUpon   Add to Technorati Technorati    What's this?

Relevant Articles

Diagnosis-specific sickness absence as a predictor of mortality: the Whitehall II prospective cohort study
Jenny Head, Jane E Ferrie, Kristina Alexanderson, Hugo Westerlund, Jussi Vahtera, and Mika Kivimäki
BMJ 2008 337: a1469. [Abstract] [Full Text] [PDF]

Incapacity benefit reform and the politics of ill health
Clare I Bambra
BMJ 2008 337: a1452. [Extract] [Full Text]

Certified sickness absence accurately indicates health differentials
BMJ 2003 327: 0. [Full Text]

This article has been cited by other articles:

  • Piha, K., Laaksonen, M., Martikainen, P., Rahkonen, O., Lahelma, E. (2009). Interrelationships between education, occupational class, income and sickness absence. Eur J Public Health 0: ckp162v1-ckp162 [Abstract] [Full text]  
  • Lawson, K. J., Noblet, A. J., Rodwell, J. J. (2009). Promoting employee wellbeing: the relevance of work characteristics and organizational justice. HEALTH PROMOT INT 24: 223-233 [Abstract] [Full text]  
  • Melchior, M., Ferrie, J. E., Alexanderson, K., Goldberg, M., Kivimaki, M., Singh-Manoux, A., Vahtera, J., Westerlund, H., Zins, M., Head, J. (2009). Using Sickness Absence Records to Predict Future Depression in a Working Population: Prospective Findings From the GAZEL Cohort. AJPH 99: 1417-1422 [Abstract] [Full text]  
  • Gjesdal, S., Haug, K., Ringdal, P., Maeland, J. G., Hagberg, J., Roraas, T., Vollset, S. E., Alexanderson, K. (2009). Sickness absence with musculoskeletal or mental diagnoses, transition into disability pension and all-cause mortality: A 9-year prospective cohort study. Scand J Public Health 37: 387-394 [Abstract]  
  • Hansen, C D, Andersen, J H (2009). Sick at work--a risk factor for long-term sickness absence at a later date?. J. Epidemiol. Community Health 63: 397-402 [Abstract] [Full text]  
  • Suoyrjo, H, Oksanen, T, Hinkka, K, Kivimaki, M, Klaukka, T, Pentti, J, Vahtera, J (2009). The effectiveness of vocationally oriented multidisciplinary intervention on sickness absence and early retirement among employees at risk: an observational study. Occup. Environ. Med. 66: 235-242 [Abstract] [Full text]  
  • Lund, T, Kivimaki, M, Christensen, K B, Labriola, M (2009). Socio-economic differences in the association between sickness absence and mortality: the prospective DREAM study of Danish private sector employees. Occup. Environ. Med. 66: 150-153 [Abstract] [Full text]  
  • Saastamoinen, P, Laaksonen, M, Lahelma, E, Leino-Arjas, P (2009). The effect of pain on sickness absence among middle-aged municipal employees. Occup. Environ. Med. 66: 131-136 [Abstract] [Full text]  
  • Ferrie, J E, Vahtera, J, Kivimaki, M, Westerlund, H, Melchior, M, Alexanderson, K, Head, J, Chevalier, A, Leclerc, A, Zins, M, Goldberg, M, Singh-Manoux, A (2009). Diagnosis-specific sickness absence and all-cause mortality in the GAZEL study. J. Epidemiol. Community Health 63: 50-55 [Abstract] [Full text]  
  • Kivimaki, M, Head, J, Ferrie, J E, Singh-Manoux, A, Westerlund, H, Vahtera, J, Leclerc, A, Melchior, M, Chevalier, A, Alexanderson, K, Zins, M, Goldberg, M (2008). Sickness absence as a prognostic marker for common chronic conditions: analysis of mortality in the GAZEL study. Occup. Environ. Med. 65: 820-826 [Abstract] [Full text]  
  • Overland, S, Glozier, N, Henderson, M, Maeland, J G, Hotopf, M, Mykletun, A (2008). Health status before, during and after disability pension award: the Hordaland Health Study (HUSK). Occup. Environ. Med. 65: 769-773 [Abstract] [Full text]  
  • Anema, J. R, Beek, A. J v. d. (2008). Medically certified sickness absence. BMJ 337: a1174-a1174 [Full text]  
  • Head, J., Ferrie, J. E, Alexanderson, K., Westerlund, H., Vahtera, J., Kivimaki, M. (2008). Diagnosis-specific sickness absence as a predictor of mortality: the Whitehall II prospective cohort study. BMJ 337: a1469-a1469 [Abstract] [Full text]  
  • Gjesdal, S., Ringdal, P. R., Haug, K., Maeland, J. G., Vollset, S. E., Alexanderson, K. (2008). Mortality after long-term sickness absence: prospective cohort study. Eur J Public Health 18: 517-521 [Abstract] [Full text]  
  • Bambra, C. I (2008). Incapacity benefit reform and the politics of ill health. BMJ 337: a1452-a1452 [Full text]  
  • Tuchsen, F., Christensen, K. B., Lund, T. (2008). Shift work and sickness absence. Occup Med (Lond) 58: 302-304 [Abstract] [Full text]  
  • Wynn, P., Low, A. (2008). The effect of social deprivation on local authority sickness absence rates. Occup Med (Lond) 58: 263-267 [Abstract] [Full text]  
  • Virtanen, P, Oksanen, T, Kivimaki, M, Virtanen, M, Pentti, J, Vahtera, J (2008). Work stress and health in primary health care physicians and hospital physicians. Occup. Environ. Med. 65: 364-366 [Abstract] [Full text]  
  • Laaksonen, M, Martikainen, P, Rahkonen, O, Lahelma, E (2008). Explanations for gender differences in sickness absence: evidence from middle-aged municipal employees from Finland. Occup. Environ. Med. 65: 325-330 [Abstract] [Full text]  
  • Vahtera, J., Kivimaki, M. (2008). Reducing sickness absence in occupational settings. Occup. Environ. Med. 65: 219-220 [Full text]  
  • Kivimaki, M, Ferrie, J E, Shipley, M J, Vahtera, J, Singh-Manoux, A, Marmot, M G, Head, J (2008). Low medically certified sickness absence among employees with poor health status predicts future health improvement: the Whitehall II study. Occup. Environ. Med. 65: 208-210 [Abstract] [Full text]  
  • Suoyrjo, H, Hinkka, K, Oksanen, T, Kivimaki, M, Klaukka, T, Pentti, J, Vahtera, J (2008). Effects of multidisciplinary inpatient rehabilitation for chronic back or neck pain: a register-linkage study of sickness absences and analgesic purchases in an occupational cohort. Occup. Environ. Med. 65: 179-184 [Abstract] [Full text]  
  • Lund, T., Kivimaki, M., Labriola, M., Villadsen, E., Christensen, K. B. (2008). Using administrative sickness absence data as a marker of future disability pension: the prospective DREAM study of Danish private sector employees. Occup. Environ. Med. 65: 28-31 [Abstract] [Full text]  
  • Voss, M, Stark, S, Alfredsson, L, Vingard, E, Josephson, M (2008). Comparisons of self-reported and register data on sickness absence among public employees in Sweden. Occup. Environ. Med. 65: 61-67 [Abstract] [Full text]  
  • Taimela, S., Laara, E., Malmivaara, A., Tiekso, J., Sintonen, H., Justen, S., Aro, T. (2007). Self-reported health problems and sickness absence in different age groups predominantly engaged in physical work. Occup. Environ. Med. 64: 739-746 [Abstract] [Full text]  
  • Kivimaki, M., Vahtera, J., Elovainio, M., Virtanen, M., Siegrist, J. (2007). Effort-reward imbalance, procedural injustice and relational injustice as psychosocial predictors of health: complementary or redundant models?. Occup. Environ. Med. 64: 659-665 [Abstract] [Full text]  
  • Morren, M., Dirkzwager, A. J.E., Kessels, F. J.M., Yzermans, C. J. (2007). The influence of a disaster on the health of rescue workers: a longitudinal study. CMAJ 176: 1279-1283 [Abstract] [Full text]  
  • Kivimaki, M, Leino-Arjas, P, Kaila-Kangas, L, Virtanen, M, Elovainio, M, Puttonen, S, Keltikangas-Jarvinen, L, Pentti, J, Vahtera, J (2007). Increased absence due to sickness among employees with fibromyalgia. Ann Rheum Dis 66: 65-69 [Abstract] [Full text]  
  • Roelen, C. A. M., van der Pol, T. R., Koopmans, P. C., Groothoff, J. W. (2006). Identifying workers at risk of sickness absence by questionnaire. Occup Med (Lond) 56: 442-446 [Abstract] [Full text]  
  • Ala-Mursula, L, Vahtera, J, Kouvonen, A, Vaananen, A, Linna, A, Pentti, J, Kivimaki, M (2006). Long hours in paid and domestic work and subsequent sickness absence: does control over daily working hours matter?. Occup. Environ. Med. 63: 608-616 [Abstract] [Full text]  
  • Benavides, F G (2006). Ill health, social protection, labour relations, and sickness absence.. Occup. Environ. Med. 63: 228-229 [Full text]  
  • Virtanen, M, Kivimaki, M, Vahtera, J, Elovainio, M, Sund, R, Virtanen, P, Ferrie, J E (2006). Sickness absence as a risk factor for job termination, unemployment, and disability pension among temporary and permanent employees.. Occup. Environ. Med. 63: 212-217 [Abstract] [Full text]  
  • Vahtera, J., Kivimaki, M., Vaananen, A., Linna, A., Pentti, J., Helenius, H., Elovainio, M. (2006). Sex differences in health effects of family death or illness: are women more vulnerable than men?. Psychosom. Med. 68: 283-291 [Abstract] [Full text]  
  • Head, J., Kivimaki, M., Martikainen, P., Vahtera, J., Ferrie, J. E, Marmot, M. G (2006). Influence of change in psychosocial work characteristics on sickness absence: the Whitehall II study. J. Epidemiol. Community Health 60: 55-61 [Abstract] [Full text]  
  • Ballard, T J, Romito, P, Lauria, L, Vigiliano, V, Caldora, M, Mazzanti, C, Verdecchia, A (2006). Self perceived health and mental health among women flight attendants. Occup. Environ. Med. 63: 33-38 [Abstract] [Full text]  
  • Virtanen, M., Kivimaki, M., Elovainio, M., Virtanen, P., Vahtera, J. (2005). Local economy and sickness absence: prospective cohort study. J. Epidemiol. Community Health 59: 973-978 [Abstract] [Full text]  
  • Kivimaki, M., Ferrie, J. E., Brunner, E., Head, J., Shipley, M. J., Vahtera, J., Marmot, M. G. (2005). Justice at Work and Reduced Risk of Coronary Heart Disease Among Employees: The Whitehall II Study. Arch Intern Med 165: 2245-2251 [Abstract] [Full text]  
  • Ala-Mursula, L., Vahtera, J., Linna, A., Pentti, J., Kivimaki, M. (2005). Employee worktime control moderates the effects of job strain and effort-reward imbalance on sickness absence: the 10-town study. J. Epidemiol. Community Health 59: 851-857 [Abstract] [Full text]  
  • Abasolo, L., Blanco, M., Bachiller, J., Candelas, G., Collado, P., Lajas, C., Revenga, M., Ricci, P., Lazaro, P., Aguilar, M. D., Vargas, E., Fernandez-Gutierrez, B., Hernandez-Garcia, C., Carmona, L., Jover, J. A. (2005). A Health System Program To Reduce Work Disability Related to Musculoskeletal Disorders. ANN INTERN MED 143: 404-414 [Abstract] [Full text]  
  • Ferrie, J E, Kivimaki, M, Head, J, Shipley, M J, Vahtera, J, Marmot, M G (2005). A comparison of self-reported sickness absence with absences recorded in employers' registers: evidence from the Whitehall II study. Occup. Environ. Med. 62: 74-79 [Abstract] [Full text]  
  • Kivimaki, M, Vahtera, J, Head, J, Ferrie, J E (2005). Are sickness absence frequencies in the study of EU countries underestimates?. Occup. Environ. Med. 62: 133-133 [Full text]  
  • Gimeno, D, Amick, B C III, Benavides, F G, Benach, J (2005). Authors' reply. Occup. Environ. Med. 62: 133-134 [Full text]  
  • Kivimaki, M., Head, J., Ferrie, J. E., Hemingway, H., Shipley, M. J., Vahtera, J., Marmot, M. G. (2005). Working While Ill as a Risk Factor for Serious Coronary Events: The Whitehall II Study. AJPH 95: 98-102 [Abstract] [Full text]  
  • Vaananen, A., Kalimo, R., Toppinen-Tanner, S., Mutanen, P., Peiro, J. M., Kivimaki, M., Vahtera, J. (2004). Role clarity, fairness, and organizational climate as predictors of sickness absence: A prospective study in the private sector. Scand J Public Health 32: 426-434 [Abstract]  
  • Kivimaki, M., Ferrie, J. E, Head, J., Shipley, M. J, Vahtera, J., Marmot, M. G (2004). Organisational justice and change in justice as predictors of employee health: the Whitehall II study. J. Epidemiol. Community Health 58: 931-937 [Abstract] [Full text]  
  • Kivimaki, M., Forma, P., Wikstrom, J., Halmeenmaki, T., Pentti, J., Elovainio, M., Vahtera, J. (2004). Sickness absence as a risk marker of future disability pension: the 10-town study. J. Epidemiol. Community Health 58: 710-711 [Full text]  
  • Vahtera, J., Kivimaki, M., Pentti, J., Linna, A., Virtanen, M., Virtanen, P., Ferrie, J. E (2004). Organisational downsizing, sickness absence, and mortality: 10-town prospective cohort study. BMJ 328: 555- [Abstract] [Full text]  

Rapid Responses:

Read all Rapid Responses

Sick certificaties in General Practice
Francesco Carelli
bmj.com, 19 Aug 2003 [Full text]
Whitehall study is often quoted but what has changed?
susanne McCabe
bmj.com, 21 Aug 2003 [Full text]



Access jobs at BMJ Careers
Whats new online at Student 

BMJ