BMJ 2003;326:1057 (17 May), doi:10.1136/bmj.326.7398.1057
Paper
Environmental tobacco smoke and tobacco related mortality in a prospective study of Californians, 1960-98
James E Enstrom, researcher1,
Geoffrey C Kabat, associate professor2
1 School of Public Health, University of California, Los Angeles, CA 90095-1772,
USA,
2 Department of Preventive Medicine, State University of New York, Stony Brook,
NY 11794-8036, USA
Correspondence to: J E Enstrom
jenstrom{at}ucla.edu
Objective To measure the relation between environmental tobacco
smoke, as estimated by smoking in spouses, and long term mortality from
tobacco related disease.
Design Prospective cohort study covering 39 years.
Setting Adult population of California, United States.
Participants 118 094 adults enrolled in late 1959 in the American
Cancer Society cancer prevention study (CPS I), who were followed until 1998.
Particular focus is on the 35 561 never smokers who had a spouse in the study
with known smoking habits.
Main outcome measures Relative risks and 95% confidence intervals
for deaths from coronary heart disease, lung cancer, and chronic obstructive
pulmonary disease related to smoking in spouses and active cigarette
smoking.
Results For participants followed from 1960 until 1998 the age
adjusted relative risk (95% confidence interval) for never smokers married to
ever smokers compared with never smokers married to never smokers was 0.94
(0.85 to 1.05) for coronary heart disease, 0.75 (0.42 to 1.35) for lung
cancer, and 1.27 (0.78 to 2.08) for chronic obstructive pulmonary disease
among 9619 men, and 1.01 (0.94 to 1.08), 0.99 (0.72 to 1.37), and 1.13 (0.80
to 1.58), respectively, among 25 942 women. No significant associations were
found for current or former exposure to environmental tobacco smoke before or
after adjusting for seven confounders and before or after excluding
participants with pre-existing disease. No significant associations were found
during the shorter follow up periods of 1960-5, 1966-72, 1973-85, and
1973-98.
Conclusions The results do not support a causal relation between
environmental tobacco smoke and tobacco related mortality, although they do
not rule out a small effect. The association between exposure to environmental
tobacco smoke and coronary heart disease and lung cancer may be considerably
weaker than generally believed.
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- Thank you
- Mark W. Volovar
bmj.com, 9 Sep 2003
[Full text]
- Second-Hand Smokescreen
- Hugh McGrath Jr.
bmj.com, 16 Sep 2003
[Full text]
- Family history?
- yogi sehgal
bmj.com, 25 Sep 2003
[Full text]
- Smoking and lung cancer: dose-response and combined exposure i.e. asbestos
- John H. Lange
bmj.com, 29 Sep 2003
[Full text]
- Re: Re: Re: Inverse effect can be explained
- Wiel Maessen
bmj.com, 30 Nov 2003
[Full text]
- Public Health Advocacy and its Five Ps
- Niyi Awofeso
bmj.com, 3 Dec 2003
[Full text]
- A question...
- C.A. Caldwell
bmj.com, 11 Dec 2003
[Full text]
- Re: A question...
- Adam Jacobs
bmj.com, 13 Dec 2003
[Full text]
- Re: Re: A question...
- Pete Petrakis, Ph.D., M.P.H.
bmj.com, 14 Dec 2003
[Full text]
- Re: Re: Re: A question...
- Adam Jacobs
bmj.com, 15 Dec 2003
[Full text]
- Re: Re: Re: Re: A question...
- Pete Petrakis, Ph.D., M.P.H.
bmj.com, 16 Dec 2003
[Full text]
- Re: Re: Re: Re: A question...
- C.A. Caldwell
bmj.com, 16 Dec 2003
[Full text]
- Re: Re: Re: Re: Re: A question...
- Pete Petrakis, Ph.D., M.P.H.
bmj.com, 17 Dec 2003
[Full text]
- Re: Re: Re: Re: Re: Re: A question...
- C.A. Caldwell
bmj.com, 24 Dec 2003
[Full text]
- Re: Re: Re: Re: A question...
- Wiel M Maessen
bmj.com, 15 Jan 2004
[Full text]
- Re. Re. Re. Re.....
- Gio B. Gori
bmj.com, 21 Jan 2004
[Full text]
- Re: Why am I dying from lung cancer caused by second-hand smoke?
- lynda duguay
bmj.com, 3 Jul 2004
[Full text]
- A Sociological Study of the Responses to Enstrom & Kabat
- Sheldon B. Ungar, et al.
bmj.com, 17 Dec 2004
[Full text]
- Environmental tobacco smoke: formulating public health policy for environmental carcinogens
- Morris Greenberg
bmj.com, 30 Aug 2005
[Full text]
- Re: Six Key Issues
- Belinda Cunnison
bmj.com, 5 Dec 2005
[Full text]
- Updated Meta-Analysis on ETS and CHD Mortality in the US
- James E Enstrom, et al.
bmj.com, 24 Jan 2006
[Full text]
- Enstrom & Kabat's Exposure Assessment Flawed
- James L. Repace
bmj.com, 25 Jan 2006
[Full text]
- Re: Enstrom & Kabat's Exposure Assessment Flawed
- Walt Cody
bmj.com, 18 Mar 2006
[Full text]
- Professor Sir Richard Peto and the House of Lords
- James E Enstrom
bmj.com, 26 Aug 2006
[Full text]
- Is the goal of TC to reduce mortality, or to protect the consensus view
- Kevin M. Mulvina
bmj.com, 15 Aug 2006
[Full text]
- Defending Legitimate Epidemiologic Research
- James E. Enstrom
bmj.com, 27 Sep 2006
[Full text]
- Risk and Cotinine: A reply to Mr. Cody
- James L. Repace
bmj.com, 29 Sep 2006
[Full text]
- Re: Risk and Cotinine: A reply to Mr. Cody
- Kevin Mulvina
bmj.com, 24 Nov 2006
[Full text]
- General response
- David C Atherton
bmj.com, 27 May 2007
[Full text]
- Combating Lysenko Pseudoscience
- James E Enstrom, et al.
bmj.com, 16 Oct 2007
[Full text]
- Re: Combating Lysenko Pseudoscience
- Kamal Chaouachi
bmj.com, 27 Oct 2007
[Full text]
- Let Us Ban Smoking Bans
- kerry p. labat junior
bmj.com, 22 Nov 2007
[Full text]
- The real threat to epidemiology's integrity
- William L Holden
bmj.com, 19 Jan 2008
[Full text]
- The 3,000 claim
- thomas r knapp
bmj.com, 6 Feb 2008
[Full text]
- A clear response from an insider
- Richard A. Marden
bmj.com, 7 Feb 2008
[Full text]