BMJ 2002;324:1254 ( 25 May )

Primary care

General practice based intervention to prevent repeat episodes of deliberate self harm: cluster randomised controlled trial

Olive Bennewith, research associatea Nigel Stocks, clinical lecturera David Gunnell, senior lecturer in epidemiology and public healthb Tim J Peters, reader in medical statisticsb Mark O Evans, lecturer in psychiatryc Deborah J Sharp, professor of primary carea

a Division of Primary Health Care, University of Bristol, Bristol BS6 6JL, b Department of Social Medicine, University of Bristol, c Division of Psychiatry, University of Bristol

Correspondence to: D Sharp debbie.sharp{at}bristol.ac.uk

Objectives: To evaluate the impact of an intervention based in general practice on the incidence of repeat episodes of deliberate self harm.
Design: Cluster randomised controlled trial in which 98 general practices were assigned in equal numbers to an intervention or a control group. The intervention comprised a letter from the general practitioner inviting the patient to consult, and guidelines on assessment and management of deliberate self harm for the general practitioner to use in consultations. Control patients received usual general practitioner care.
Setting: General practices within Avon, Wiltshire, and Somerset Health Authorities, whose patients lived within the catchment area of four general hospitals in Bristol and Bath.
Participants: 1932 patients registered with the study practices who had attended accident and emergency departments at one of the four hospitals after an episode of deliberate self harm.
Main outcome measures: Primary outcome was occurrence of a repeat episode of deliberate self harm in the 12 months after the index episode. Secondary outcomes were number of repeat episodes and time to first repeat.
Results: The incidence of repeat episodes of deliberate self harm was not significantly different for patients in the intervention group compared with the control group (odds ratio 1.2, 95% confidence interval 0.9 to 1.5). Similar findings were obtained for the number of repeat episodes and time to first repeat. Subgroup analyses indicated that there was no differential effect of the intervention according to patient's sex (P=0.51) or method used to cause deliberate self harm (P=0.64). The treatment seemed to be beneficial for people with a history of deliberate self harm, but it was associated with an adverse effect in people for whom the index episode was their first episode (interaction P=0.017).
Conclusions: An invitation to consult, sent by the general practitioner of patients who have deliberately harmed themselves, and the use of management guidelines during any subsequent consultation did not reduce the incidence of repeat self harm. A subgroup analysis that indicated that patients who had previously harmed themselves benefited from the intervention was inconsistent with previous evidence and should be treated with caution. More research is needed on how to manage patients who deliberately harm themselves, to reduce the incidence of repeat episodes.

What is already known on this topic
About two thirds of patients consult their general practitioner in the three months after an episode of deliberate self harm

There have been no previous large scale randomised controlled trials of general practice based interventions aimed at reducing the incidence of repeat episodes of deliberate self harm

What this study adds
An intervention comprising an invitation to consult from a patient's general practitioner and by the use of guidelines for the assessment and management of deliberate self harm in a subsequent consultation does not reduce the incidence of repeat episodes of deliberate self harm




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