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Johann Steurer Horten-Zentrum für
praxisorientierte Forschung und Wissenstransfer, Universitätsspital
Zürich, Bolleystrasse 40, Postfach Nord, CH-8091 Zurich, Switzerland
Correspondence to: J Steurer johann.steurer{at}dim.usz.ch
Objective:
To assess the extent to which different
forms of summarising diagnostic test information influence general
practitioners' ability to estimate disease probabilities.
What is already known on this topic
Doctors tend to overestimate information derived from such tests and
underestimate information from a patient's clinical history Most primary research on diagnostic accuracy is reported using
sensitivity and specificity or likelihood ratios What this study adds
When presented with a positive result alone they grossly overestimated
its value Adding information on the test's sensitivity and specificity moderated
these overestimates, and expressing the same numerical information as a
positive likelihood ratio in simple, non-technical language brought the
estimates still closer to their true values
Design:
Controlled questionnaire study.
Setting:
Three Swiss conferences in continuous medical education.
Participants:
263 general practitioners.
Intervention:
Questionnaire with multiple choice
questions about terms of test accuracy and a clinical vignette with the results of a diagnostic test described in three different ways (test
result only, test result plus test sensitivity and specificity, test
result plus the positive likelihood ratio presented in plain language).
Main outcome measures:
Doctors' knowledge and
application of terms of test accuracy and estimation of disease
probability in the clinical vignette.
Results:
The correct definitions for sensitivity and predictive value were chosen by 76% and 61% of the doctors
respectively, but only 22% chose the correct answer for the post-test
probability of a positive screening test. In the clinical vignette
doctors given the test result only overestimated its diagnostic value (median attributed likelihood ratio (aLR)=9.0, against 2.54 reported in
the literature). Providing the scan's sensitivity and specificity reduced the overestimation (median aLR=6.0) but to a lesser extent than
simple wording of the likelihood ratio (median aLR=3.0).
Conclusion:
Most general practitioners recognised the correct definitions for sensitivity and positive predictive value but
did not apply them correctly. Conveying test accuracy information in
simple, non-technical language improved their ability to estimate disease probabilities accurately.
Many doctors confuse the sensitivity of clinical tests and their
positive predictive value
In a cohort of experienced Swiss general practitioners most were unable
to interpret correctly numerical information on the diagnostic accuracy
of a screening test
© BMJ 2002
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