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Streptokinase versus alteplase and other treatments for acute and delayed thrombolysis of blood stains in clothing
C K Pager Royal Prince Alfred Hospital, Sydney,
Australia 2050
ckpager{at}bigfoot.com
Objective:
To assess the usefulness of heparin,
alteplase, and streptokinase in removing blood stains.
Design:
Randomised controlled trial.
Setting:
Hospital laundry.
Interventions:
Blood stains were allocated to
treatment with alteplase, streptokinase, heparin, a commercial
enzymatic stain remover, or no treatment at all after three or seven
hours and then washed in hot or cold water two hours later.
Results:
Both hot water and early treatment were
strongly associated with improved stain removal. All four treatments
were associated with a worse outcome than no treatment at all, although for streptokinase this trend did not reach significance. The commercial stain remover gave the worst results of all treatments tested.
Conclusions:
Contrary to popular wisdom, hot water is
much more effective than cold in removing blood stains.
Methodologically rigorous research and evidence based principles are
needed within the laundry industry, and the role of thrombolytic drugs
should be assessed further.
© BMJ 2000
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(2001). PREWASH LABS I: Prospective, Randomized Evaluation of Water, Alteplase, Streptokinase, and Heparin for Laundering Blood Stains I. JWatch Emergency Med.
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