BMJ 2000;320:550-554 ( 26 February )

General Practice

Randomised trial of monitoring, feedback, and management of care by telephone to improve treatment of depression in primary care

Gregory E Simon, investigator,  Michael VonKorff, investigator,  Carolyn Rutter, investigator,  Edward Wagner, investigator. 

Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA

Correspondence to: G Simon simon.g{at}ghc.org

Objective: To test the effectiveness of two programmes to improve the treatment of acute depression in primary care.
Design: Randomised trial.
Setting: Primary care clinics in Seattle.
Patients: 613 patients starting antidepressant treatment.
Intervention: Patients were randomly assigned to continued usual care or one of two interventions: feedback only and feedback plus care management. Feedback only comprised feedback and algorithm based recommendations to doctors on the basis of data from computerised records of pharmacy and visits. Feedback plus care management included systematic follow up by telephone, sophisticated treatment recommendations, and practice support by a care manager.
Main outcome measures: Blinded interviews by telephone 3 and 6 months after the initial prescription included a 20 item depression scale from the Hopkins symptom checklist and the structured clinical interview for the current DSM-IV depression module. Visits, antidepressant prescriptions, and overall use of health care were assessed from computerised records.
Results: Compared with usual care, feedback only had no significant effect on treatment received or patient outcomes. Patients receiving feedback plus care management had a higher probability of both receiving at least moderate doses of antidepressants (odds ratio 1.99, 95% confidence interval 1.23 to 3.22) and a 50% improvement in depression scores on the symptom checklist (2.22, 1.31 to 3.75), lower mean depression scores on the symptom checklist at follow up, and a lower probability of major depression at follow up (0.46, 0.24 to 0.86). The incremental cost of feedback plus care management was about $80 (£50) per patient.
Conclusions: Monitoring and feedback to doctors yielded no significant benefits for patients in primary care starting antidepressant treatment. A programme of systematic follow up and care management by telephone, however, significantly improved outcomes at modest cost.

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• Gilbody, S M, Whitty, P M, Grimshaw, J M, Thomas, R E (2003). Improving the detection and management of depression in primary care. Qual Saf Health Care 12: 149-155 [Abstract] [Full text]  
• Horvitz-Lennon, M., Normand, S.-L. T., Frank, R. G., Goldman, H. H. (2003). "Usual Care" for Major Depression in the 1990s: Characteristics and Expert-Estimated Outcomes. Am. J. Psychiatry 160: 720-726 [Abstract] [Full text]  
• Dietrich, A. J., Oxman, T. E., Burns, M. R., Winchell, C. W., Chin, T. (2003). Application of a Depression Management Office System in Community Practice: A Demonstration. J Am Board Fam Med 16: 107-114 [Abstract] [Full text]  
• Rothman, A. A., Wagner, E. H. (2003). Chronic Illness Management: What Is the Role of Primary Care?. ANN INTERN MED 138: 256-261 [Abstract] [Full text]  
• Pincus, H. A. (2003). The Future of Behavioral Health and Primary Care: Drowning in the Mainstream or Left on the Bank?. Psychosomatics 44: 1-11 [Full text]  
• Casalino, L., Gillies, R. R., Shortell, S. M., Schmittdiel, J. A., Bodenheimer, T., Robinson, J. C., Rundall, T., Oswald, N., Schauffler, H., Wang, M. C. (2003). External Incentives, Information Technology, and Organized Processes to Improve Health Care Quality for Patients With Chronic Diseases. JAMA 289: 434-441 [Abstract] [Full text]  
• McLaren, P. (2003). Telemedicine and telecare: what can it offer mental health services?. Adv. Psychiatr. Treat. 9: 54-61 [Abstract] [Full text]  
• Oxman, T. E., Dietrich, A. J., Williams, J. W. Jr., Kroenke, K. (2002). A Three-Component Model for Reengineering Systems for the Treatment of Depression in Primary Care. Psychosomatics 43: 441-450 [Abstract] [Full text]  
• Sherman, S. E (2002). Review: screening for depression reduces persistent depression. Evid. Based Med. 7: 178-178 [Full text]  
• Weingarten, S. R, Henning, J. M, Badamgarav, E., Knight, K., Hasselblad, V., Gano, A. Jr, Ofman, J. J (2002). Interventions used in disease management programmes for patients with chronic illness---which ones work? Meta-analysis of published reports. BMJ 325: 925-925 [Abstract] [Full text]  
• Rost, K., Nutting, P., Smith, J. L, Elliott, C. E, Dickinson, M. (2002). Managing depression as a chronic disease: a randomised trial of ongoing treatment in primary care. BMJ 325: 934-934 [Abstract] [Full text]  
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• Oxman, T. E., Sengupta, A. (2002). Treatment of Minor Depression. AJGP 10: 256-264 [Abstract] [Full text]  
• Simon, G. (2001). Choosing a First-Line Antidepressant: Equal on Average Does Not Mean Equal for Everyone. JAMA 286: 3003-3004 [Full text]  
• Simon, G. E., Katon, W. J., VonKorff, M., Unutzer, J., Lin, E. H.B., Walker, E. A., Bush, T., Rutter, C., Ludman, E. (2001). Cost-Effectiveness of a Collaborative Care Program for Primary Care Patients With Persistent Depression. Am. J. Psychiatry 158: 1638-1644 [Abstract] [Full text]  
• Unutzer, J., Rubenstein, L., Katon, W. J., Tang, L., Duan, N., Lagomasino, I. T., Wells, K. B. (2001). Two-Year Effects of Quality Improvement Programs on Medication Management for Depression. Arch Gen Psychiatry 58: 935-942 [Abstract] [Full text]  
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• Peveler, R., Kendrick, T. (2001). Treatment delivery and guidelines in primary care: Depression and public health. Br Med Bull 57: 193-206 [Abstract] [Full text]  
• Dowrick, C. (2001). Advances in psychiatric treatment in primary care. Adv. Psychiatr. Treat. 7: 1-8 [Full text]  
• Whooley, M. A., Simon, G. E. (2000). Managing Depression in Medical Outpatients. NEJM 343: 1942-1950 [Full text]  
• Williams, J. W Jr (2000). Feedback to physicians plus telephone care management improved outcomes in primary care patients with depression. Evid. Based Ment. Health 3: 124-124 [Full text]  
• Lin, E. H. B., VonKorff, M., Russo, J., Katon, W., Simon, G. E., Unutzer, J., Bush, T., Walker, E., Ludman, E. (2000). Can Depression Treatment in Primary Care Reduce Disability?: A Stepped Care Approach. Arch Fam Med 9: 1052-1058 [Abstract] [Full text]  
• (2000). Other articles noted. Evid. Based Nurs. 3: 106-112 [Full text]  
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• Dietrich, A. J., Katzelnick, D., Simon, G., Pearson, S., Manning, W., Kobak, K. (2000). Depression Management Programs. Arch Fam Med 9: 689-670 [Full text]  
• Katon, W. (2000). Improvement of Outcomes in Chronic Illness. Arch Fam Med 9: 709-711 [Full text]  
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