Relation of vagotomy to subsequent risk of lung cancer: population based cohort study

BMJ 1998;316:518-519 (14 February)

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Relation of vagotomy to subsequent risk of lung cancer: population based cohort study

Anders Ekbom, associate professor,^a Göran Lundegårdh, physician,^a Joseph K McLaughlin, epidemiologist,^b Olof Nyrén, associate professor ^a

^a Department of Medical Epidemiology, Karolinska Institute, PO Box 281, S-171 77, Stockholm, Sweden, ^b International Epidemiology Institute, Rockville, MA 20850, USA

Correspondence to: Professor Ekbom Anders.Ekbom@mep.ki.se

Smoking increases the risk of peptic ulcer disease and alsoadversely affects its course. Both pharmacological and surgicaltreatments will lead to a relief from the symptoms of the disease. We analysed to what extent such potential relief would affectthe subsequent risk of lung cancer in patients who had had avagotomy for peptic ulcer disease, compared with patients withthe disease who were treated without surgery.

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