BMJ 1997;314:1439 (17 May)

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Age specific trends in asthma mortality in England and Wales, 1983-95: results of an observational study

M J Campbell, reader in medical statistics,a G R Cogman, MSc student,a S T Holgate, MRC professor of immunopharmacology,b S L Johnston, senior lecturer in medicine b

a Southampton University Department of Medical Statistics and Computing, Southampton General Hospital, Southampton S016 6YD, b Southampton University Department of Medicine, Southampton General Hospital

Correspondence to: Dr Campbell m.j.campbell@soton.ac.uk

Objective: To determine trends in asthma mortality by age group in England and Wales during 1983-95.
Design: Observational study.
Setting: England and Wales.
Subjects: All deaths classified as having an underlying cause of asthma registered from 1 January 1983 to 31 December 1995.
Main outcome measure: Time trends for age specific asthma deaths.
Results: Deaths in the age group 5-14 years showed an irregular downward trend during 1983-95; deaths in the age groups 15-44, 45-64, and 65-74 years peaked before 1989 and then showed a downward trend; and deaths in the age group 75-84 years peaked between 1988 and 1993 and subsequently dropped. Trends were: age group 5-14 years, 6% (95% confidence interval 3% to 9%); 15-44 years, 6% (5% to 7%); 45-64 years, 5% (4% to 6%); 65-74 years, 2% (1% to 3%). Deaths in the 75-84 and 85 and over categories plateaued.
Conclusions: There are downward trends in asthma mortality in Britain, which may be due to increased use of prophylactic treatment.

Key messages

  • Asthma mortality in England and Wales is dropping by about 6% a year in people aged 5-64 years

  • It is changing only slowly in those aged 65 and over


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