BMJ 1997;314:789 (15 March)

Papers

Regression analysis of recent changes in cardiovascular morbidity and mortality in the netherlands

Luc Bonneux, medical epidemiologist,a Caspar W N Looman, biostatistician,a Jan J Barendregt, mathematical economist,a Paul J Van der Maas, professor in public health a

a Department of Public Health Erasmus University Rotterdam PO Box 1738 3000 DR Rotterdam Netherlands

Correspondence to: Dr Bonneux bonneux@mgz.fgg.eur.nl

Objectives: To test whether recent declines in mortality from coronary heart disease were associated with increased mortality from other cardiovascular diseases.
Design: Poisson regression analysis of national data on causes of death and hospital discharges.
Setting and subjects: Population of the Netherlands, 1969-93.
Main outcome measures: Annual changes in mortality from coronary heart disease, stroke, and other cardiovascular diseases and annual changes in hospital discharge rates for acute coronary events, stroke, and congestive heart failures.
Results: Patterns of cardiovascular mortality changed abruptly in 1987-93. Annual decline in mortality from coronary heart disease increased sharply for women and men: from -1.9% (95% confidence interval -2.2% to -1.6%) and -1.7% (-1.9% to -1.4%) respectively in 1979-86 to -3.1% (-3.5% to -2.6%) and -4.2% (-4.6% to -3.9%) in 1987-93. The longstanding decline in mortality from stroke levelled off: from annual change of -3.3% (-3.7% to -2.8%) and -3.2% (-3.7% to -2.8%) in 1979-86 to -0.1% (-0.7% to 0.4%) and -1.1% (-1.7% to -0.5%) in 1987-93. Mortality from other cardiovascular diseases, however, started to increase: from -2.0% (-2.4% to -1.6%) and -0.2% (-0.5% to 0.2%) in 1979-86 to 1.5% (1.0% to 2.0%) and 1.9% (1.5% to 2.3%) in 1987-93. Hospital discharge rates for acute coronary heart disease, congestive heart failure, and stroke increased during 1980-6. During 1987-93 discharge rates for stroke and coronary heart disease stabilised but rates for congestive heart failure increased.
Conclusion: Improved management of coronary heart disease seems to have reduced mortality, but some of the gains are lost to deaths from stroke and other cardiovascular diseases. The increasing numbers of patients with coronary heart disease who survive will increase demands on health services for long term care.

Key messages

  • In the Netherlands, mortality from coronary heart disease has decreased in recent years, but mortality from other cardiovascular diseases has increased

  • The longstanding decline in mortality from stroke has stopped, and hospital discharge rates of patients with a diagnosis of congestive heart failure have increased

  • The most parsimonious hypothesis explaining these changes is that increasing numbers of survivors of coronary heart disease are boosting the numbers of patients at high risk of other cardiovascular disorders

  • Health services will have to cope with more patients disabled by chronic cardiovascular disease, with their high needs for care


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to StumbleUpon StumbleUpon   Add to Technorati Technorati    What's this?

Relevant Article

Hypothesis that people with coronary heart disease are living longer is supported
P S Watson and D C Bensley
BMJ 1997 314: 1828. [Extract] [Full Text]

This article has been cited by other articles:

  • Laatikainen, T., Critchley, J., Vartiainen, E., Salomaa, V., Ketonen, M., Capewell, S. (2005). Explaining the Decline in Coronary Heart Disease Mortality in Finland between 1982 and 1997. Am J Epidemiol 162: 764-773 [Abstract] [Full text]  
  • Janssen, F, Peeters, A, Mackenbach, J P, Kunst, A E, for NEDCOM, (2005). Relation between trends in late middle age mortality and trends in old age mortality--is there evidence for mortality selection?. J. Epidemiol. Community Health 59: 775-781 [Abstract] [Full text]  
  • Struijs, J. N., van Genugten, M. L.L., Evers, S. M.A.A., Ament, A. J.H.A., Baan, C. A., van den Bos, G. A.M. (2005). Modeling the Future Burden of Stroke in the Netherlands: Impact of Aging, Smoking, and Hypertension. Stroke 36: 1648-1655 [Abstract] [Full text]  
  • Peeters, A., Bonneux, L., Barendregt, J. J., Mackenbach, J. P. (2003). Improvements in Treatment of Coronary Heart Disease and Cessation of Stroke Mortality Rate Decline. Stroke 34: 1610-1614 [Abstract] [Full text]  
  • Critchley, J A, Capewell, S (2003). Substantial potential for reductions in coronary heart disease mortality in the UK through changes in risk factor levels. J. Epidemiol. Community Health 57: 243-247 [Abstract] [Full text]  
  • Pessah-Rasmussen, H., Engstrom, G., Jerntorp, I., Janzon, L. (2003). Increasing Stroke Incidence and Decreasing Case Fatality, 1989-1998: A Study From the Stroke Register in Malmo, Sweden. Stroke 34: 913-918 [Abstract] [Full text]  
  • Muntwyler, J., Abetel, G., Gruner, C., Follath, F. (2002). One-year mortality among unselected outpatients with heart failure. Eur Heart J 23: 1861-1866 [Abstract] [Full text]  
  • McKee, M. (2002). What can health services contribute to the reduction of inequalities in health?. Scand J Public Health 30: 54-58 [Abstract]  
  • van Beeck, E. F, Borsboom, G. J., Mackenbach, J. P (2000). Economic development and traffic accident mortality in the industrialized world, 1962-1990. Int J Epidemiol 29: 503-509 [Abstract] [Full text]  
  • Nusselder, W., Mackenbach, J. (2000). Lack of improvement of life expectancy at advanced ages in The Netherlands. Int J Epidemiol 29: 140-148 [Abstract] [Full text]  
  • Reitsma, J B, Dalstra, J A A, Bonsel, G J, van der Meulen, J H P, Koster, R W, Gunning-Schepers, L J, Tijssen, J G P (1999). Cardiovascular disease in the Netherlands, 1975 to 1995: decline in mortality, but increasing numbers of patients with chronic conditions. Heart 82: 52-56 [Abstract] [Full text]  
  • Klungel, O. H., Stricker, B. H. C., Paes, A. H. P., Seidell, J. C., Bakker, A., Voko, Z., Breteler, M. M. B., Anthonius de Boer, (1999). Excess Stroke Among Hypertensive Men and Women Attributable to Undertreatment of Hypertension. Stroke 30: 1312-1318 [Abstract] [Full text]  
  • (1998). The falling mortality from coronary heart disease: a clinicopathological perspective. Heart 80: 121-126 [Abstract] [Full text]  
  • Watson, P S, Bensley, D C (1997). Hypothesis that people with coronary heart disease are living longer is supported. BMJ 314: 1828-1828 [Full text]  



Access jobs at BMJ Careers
Whats new online at Student 

BMJ