BMJ 1997;314:789 (15 March)
Papers
Regression analysis of recent changes in cardiovascular morbidity and mortality in the netherlands
Luc Bonneux,
medical
epidemiologist,a
Caspar W N Looman,
biostatistician,a
Jan J Barendregt,
mathematical
economist,a
Paul J Van der Maas,
professor
in public health aa Department of Public Health Erasmus University Rotterdam PO Box 1738 3000 DR Rotterdam Netherlands
Correspondence to: Dr Bonneux bonneux@mgz.fgg.eur.nl
Objectives: To test whether recent declines in
mortality from coronary heart disease were associated with increased mortality from other
cardiovascular diseases.
Design: Poisson regression analysis of national data
on causes of death and hospital discharges.
Setting and subjects: Population of the Netherlands,
1969-93.
Main outcome measures: Annual changes in
mortality from coronary heart disease, stroke, and other cardiovascular diseases and annual
changes in hospital discharge rates for acute coronary events, stroke, and congestive heart
failures.
Results: Patterns of cardiovascular mortality
changed abruptly in 1987-93. Annual decline in mortality from coronary heart disease
increased sharply for women and men: from -1.9% (95% confidence
interval -2.2% to -1.6%) and -1.7%
(-1.9% to -1.4%) respectively in 1979-86 to
-3.1% (-3.5% to -2.6%) and -4.2%
(-4.6% to -3.9%) in 1987-93. The longstanding decline in
mortality from stroke levelled off: from annual change of -3.3%
(-3.7% to -2.8%) and -3.2% (-3.7%
to -2.8%) in 1979-86 to -0.1% (-0.7% to
0.4%) and -1.1% (-1.7% to -0.5%) in
1987-93. Mortality from other cardiovascular diseases, however, started to increase: from
-2.0% (-2.4% to -1.6%) and -0.2%
(-0.5% to 0.2%) in 1979-86 to 1.5% (1.0% to
2.0%) and 1.9% (1.5% to 2.3%) in 1987-93. Hospital discharge
rates for acute coronary heart disease, congestive heart failure, and stroke increased during
1980-6. During 1987-93 discharge rates for stroke and coronary heart disease
stabilised but rates for congestive heart failure increased.
Conclusion: Improved management of coronary
heart disease seems to have reduced mortality, but some of the gains are lost to deaths from
stroke and other cardiovascular diseases. The increasing numbers of patients with coronary heart
disease who survive will increase demands on health services for long term care.
|
Key messages
- In the Netherlands, mortality from coronary heart disease has decreased in recent years,
but mortality from other cardiovascular diseases has increased
- The longstanding decline in mortality from stroke has stopped, and hospital discharge
rates of patients with a diagnosis of congestive heart failure have increased
- The most parsimonious hypothesis explaining these changes is that increasing numbers
of survivors of coronary heart disease are boosting the numbers of patients at high risk of other
cardiovascular disorders
- Health services will have to cope with more patients disabled by chronic cardiovascular
disease, with their high needs for care
|

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