BMJ 1997;314:705 (8 March)

Papers

Cross sectional analysis of mortality by country of birth in england and wales, 1970-92

Sarah Wild, Wellcome training fellow in clinical epidemiology,a Paul Mckeigue, senior lecturer a

a Epidemiology Unit, Department of Epidemiology and Population Sciences, London School of Hygiene & Tropical Medicine, London, WC1E 7HT

Correspondence to: Dr Wild

Objective: To compare mortalities for selected groups of immigrants with the national average.
Design: Analysis of mortality for adults aged 20-69 in 1970-2 and 1989-92 using population data from 1971 and 1991 censuses. Mortality of Scottish and Irish immigrants aged 25-74 was also compared with mortality in Scotland and Ireland for 1991.
Setting: England and Wales.
Main outcome measures: Standardised mortality ratios for deaths from all causes, ischaemic heart disease, cerebrovascular disease, lung cancer, and breast cancer.
Results: In 1989-92 mortality from all causes was higher than the national average for Scottish immigrants, by 32% for men and 36% for women; for Irish immigrants it was higher by 39% for men and 20% for women; and for Caribbean born men it was lower by 23%. Ischaemic heart disease and lung cancer accounted for 30-40% of the excess mortality in Scottish and Irish immigrants. For south Asians, excess mortality from circulatory disease was balanced by lower mortality from cancer. Standardised mortality ratios for cerebrovascular disease in 1989-92 were highest for west African immigrants (271 for men and 181 for women).
Conclusions: Widening differences in mortality ratios for migrants compared with the general population were not simply due to socioeconomic inequalities. The low mortality from all causes for Caribbean immigrants could largely be attributed to low mortality from ischaemic heart disease, which is unexplained. The excess mortality from cerebrovascular and hypertensive diseases in migrants from both west Africa and the Caribbean suggests that genetic factors underlie the susceptibility to hypertension in people of black African descent.

Key messages

  • Differences in mortality of immigrants in England and Wales widened between 1970 and 1992 and could not be explained by socioeconomic differences

  • Mortality from all causes was higher than average for Scottish and Irish immigrants, and some of the excess could be accounted for by smoking habits, reflected by increased mortality ratios for lung cancer

  • Mortality ratios for stroke and hypertension were highest in west African immigrants, indicating that better detection and treatment of hypertension is required in this group

  • Mortality from all causes was low in Caribbean immigrants, largely due to low mortality from ischaemic heart disease

  • Mortality from ischaemic heart disease remained high in south Asian immigrants and did not decline as fast as in the general population


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to StumbleUpon StumbleUpon   Add to Technorati Technorati    What's this?

Relevant Articles

Pattern recognition versus bayesian approach for diagnosis in primary care
John Fletcher and Robin Fox
BMJ 2006 332: 646. [Extract] [Full Text] [PDF]

Limitations and potential of country of birth as proxy for ethnic group
Paramjit S Gill, Raj Bhopal, Sarah Wild, and Joe Kai
BMJ 2005 330: 196. [Extract] [Full Text]

This article has been cited by other articles:

  • Banerjee, S., Biram, R., Chataway, J., Ames, D. (2009). South Asian strokes: lessons from the St Mary's stroke database. QJM 0: hcp148v1-hcp148 [Abstract] [Full text]  
  • Owen, C. G, Nightingale, C. M, Rudnicka, A. R, Cook, D. G, Ekelund, U., Whincup, P. H (2009). Ethnic and gender differences in physical activity levels among 9-10-year-old children of white European, South Asian and African-Caribbean origin: the Child Heart Health Study in England (CHASE Study). Int J Epidemiol 38: 1082-1093 [Abstract] [Full text]  
  • Sabbah, W, Tsakos, G, Sheiham, A, Watt, R G (2009). The effects of income and education on ethnic differences in oral health: a study in US adults. J. Epidemiol. Community Health 63: 516-520 [Abstract] [Full text]  
  • Gunarathne, A., Patel, J. V., Kausar, S., Gammon, B., Hughes, E. A., Lip, G. Y.H. (2009). Glycemic Status Underlies Increased Arterial Stiffness and Impaired Endothelial Function in Migrant South Asian Stroke Survivors Compared to European Caucasians: Pathophysiological Insights From the West Birmingham Stroke Project. Stroke 40: 2298-2306 [Abstract] [Full text]  
  • Bhala, N., Bhopal, R., Brock, A., Griffiths, C., Wild, S. (2009). Alcohol-related and hepatocellular cancer deaths by country of birth in England and Wales: analysis of mortality and census data. J Public Health (Oxf) 31: 250-257 [Abstract] [Full text]  
  • Gunarathne, A., Patel, J. V., Gammon, B., Gill, P. S., Hughes, E. A., Lip, G. Y.H. (2009). Ischemic Stroke in South Asians: A Review of the Epidemiology, Pathophysiology, and Ethnicity-Related Clinical Features. Stroke 40: e415-e423 [Abstract] [Full text]  
  • Zaman, M. J., Crook, A. M., Junghans, C., Fitzpatrick, N. K., Feder, G., Timmis, A. D., Hemingway, H. (2009). Ethnic differences in long-term improvement of angina following revascularization or medical management: a comparison between south Asians and white Europeans. J Public Health (Oxf) 31: 168-174 [Abstract] [Full text]  
  • Wells, J. C K (2009). Ethnic variability in adiposity and cardiovascular risk: the variable disease selection hypothesis. Int J Epidemiol 38: 63-71 [Abstract] [Full text]  
  • Mitchell, R, Gibbs, J, Tunstall, H, Platt, S, Dorling, D (2009). Factors which nurture geographical resilience in Britain: a mixed methods study. J. Epidemiol. Community Health 63: 18-23 [Abstract] [Full text]  
  • Bennett, P.C., Silverman, S., Gill, P.S., Lip, G.Y.H. (2009). Ethnicity and peripheral artery disease. QJM 102: 3-16 [Abstract] [Full text]  
  • Ramaraj, R, Chellappa, P (2008). Cardiovascular risk in South Asians. Postgrad. Med. J. 84: 518-523 [Abstract] [Full text]  
  • Zaman, M. J. MBBS MSc, Junghans, C. PhD, Sekhri, N. MBBS, Chen, R. MD PhD, Feder, G. S. MD, Timmis, A. D. MBBChir MD, Hemingway, H. MBBChir (2008). Presentation of stable angina pectoris among women and South Asian people. CMAJ 179: 659-667 [Abstract] [Full text]  
  • Elkeles, R. S., Godsland, I. F., Feher, M. D., Rubens, M. B., Roughton, M., Nugara, F., Humphries, S. E., Richmond, W., Flather, M. D., for the PREDICT Study Group, (2008). Coronary calcium measurement improves prediction of cardiovascular events in asymptomatic patients with type 2 diabetes: the PREDICT study. Eur Heart J 29: 2244-2251 [Abstract] [Full text]  
  • Russo, P., Siani, A., Miller, M. A., Karanam, S., Esposito, T., Gianfrancesco, F., Barba, G., Lauria, F., Strazzullo, P., Cappuccio, F. P. (2008). Genetic Variants of Y Chromosome Are Associated With a Protective Lipid Profile in Black Men. Arterioscler. Thromb. Vasc. Bio. 28: 1569-1574 [Abstract] [Full text]  
  • Asghar, R. J., Pratt, R. H., Kammerer, J. S., Navin, T. R. (2008). Tuberculosis in South Asians Living in the United States, 1993-2004. Arch Intern Med 168: 936-942 [Abstract] [Full text]  
  • Harding, S, Rosato, M, Teyhan, A (2008). Trends for coronary heart disease and stroke mortality among migrants in England and Wales, 1979-2003: slow declines notable for some groups. Heart 94: 463-470 [Abstract] [Full text]  
  • Gray, L., Harding, S., Reid, A. (2007). Evidence of divergence with duration of residence in circulatory disease mortality in migrants to Australia. Eur J Public Health 17: 550-554 [Abstract] [Full text]  
  • Lane, D.A., Lip, G.Y.H., Beevers, D.G. (2007). Ethnic differences in cancer incidence and mortality: the Birmingham Factory Screening Project. QJM 100: 423-431 [Abstract] [Full text]  
  • Wild, S.H., Fischbacher, C., Brock, A., Griffiths, C., Bhopal, R. (2007). Mortality from all causes and circulatory disease by country of birth in England and Wales 2001-2003. J Public Health (Oxf) 29: 191-198 [Abstract] [Full text]  
  • Khunti, K., Stone, M. A, Bankart, J., Sinfield, P. K, Talbot, D., Farooqi, A., Davies, M. J (2007). Physical activity and sedentary behaviours of South Asian and white European children in inner city secondary schools in the UK. Fam Pract 24: 237-244 [Abstract] [Full text]  
  • Murphy, C., Kanaganayagam, G. S., Jiang, B., Chowienczyk, P. J., Zbinden, R., Saha, M., Rahman, S., Shah, A. M., Marber, M. S., Kearney, M. T. (2007). Vascular Dysfunction and Reduced Circulating Endothelial Progenitor Cells in Young Healthy UK South Asian Men. Arterioscler. Thromb. Vasc. Bio. 27: 936-942 [Abstract] [Full text]  
  • (2007). Stable angina who needs revascularisation?. DTB 45: 12-16 [Abstract] [Full text]  
  • Brindle, P, May, M, Gill, P, Cappuccio, F, D'Agostino, R Sr, Fischbacher, C, Ebrahim, S (2006). Primary prevention of cardiovascular disease: a web-based risk score for seven British black and minority ethnic groups. Heart 92: 1595-1602 [Abstract] [Full text]  
  • Bhopal, R. (2006). Race and Ethnicity: Responsible Use from Epidemiological and Public Health Perspectives. J Law Med Ethics 34: 500-507  
  • Tillin, T., Forouhi, N. G., McKeigue, P. M., Chaturvedi, N. (2006). The Role of Diabetes and Components of the Metabolic Syndrome in Stroke and Coronary Heart Disease Mortality in U.K. White and African-Caribbean Populations.. Diabetes Care 29: 2127-2129 [Full text]  
  • Retnakaran, R., Hanley, A. J.G., Zinman, B. (2006). Does Hypoadiponectinemia Explain the Increased Risk of Diabetes and Cardiovascular Disease in South Asians?. Diabetes Care 29: 1950-1954 [Full text]  
  • Liew, R, Sulfi, S, Ranjadayalan, K, Cooper, J, Timmis, A D (2006). Declining case fatality rates for acute myocardial infarction in South Asian and white patients in the past 15 years. Heart 92: 1030-1034 [Abstract] [Full text]  
  • Fletcher, J., Fox, R. (2006). Pattern recognition versus bayesian approach for diagnosis in primary care.. BMJ 332: 646-646 [Full text]  
  • Saxena, S., George, J., Barber, J., Fitzpatrick, J., Majeed, A. (2006). Association of population and practice factors with potentially avoidable admission rates for chronic diseases in London: cross sectional analysis. JRSM 99: 81-89 [Abstract] [Full text]  
  • Tillin, T., Forouhi, N., McKeigue, P., Chaturvedi, N. (2005). Microalbuminuria and Coronary Heart Disease Risk in an Ethnically Diverse UK Population: A Prospective Cohort Study. J. Am. Soc. Nephrol. 16: 3702-3710 [Abstract] [Full text]  
  • Mukhopadhyay, B., Sattar, N., Fisher, M. (2005). Review: Diabetes and cardiac disease in South Asians. British Journal of Diabetes & Vascular Disease 5: 253-259 [Abstract]  
  • Sachdev, H. S, Fall, C. H., Osmond, C., Lakshmy, R., Dey Biswas, S. K, Leary, S. D, Reddy, K. S., Barker, D. J., Bhargava, S. K (2005). Anthropometric indicators of body composition in young adults: relation to size at birth and serial measurements of body mass index in childhood in the New Delhi birth cohort. Am. J. Clin. Nutr. 82: 456-466 [Abstract] [Full text]  
  • Farooq, S., Coleman, M. P (2005). Breast cancer survival in South Asian women in England and Wales. J. Epidemiol. Community Health 59: 402-406 [Abstract] [Full text]  
  • Liew, C. F., Wise, S. D., Yeo, K. P., Lee, K. O. (2005). Insulin-Like Growth Factor Binding Protein-1 Is Independently Affected by Ethnicity, Insulin Sensitivity, and Leptin in Healthy, Glucose-Tolerant Young Men. J. Clin. Endocrinol. Metab. 90: 1483-1488 [Abstract] [Full text]  
  • Gill, P. S, Bhopal, R., Wild, S., Kai, J. (2005). Limitations and potential of country of birth as proxy for ethnic group. BMJ 330: 196-196 [Full text]  
  • Khan, F. A., Zia, E., Janzon, L., Engstrom, G. (2004). Incidence of Stroke and Stroke Subtypes in Malmo, Sweden, 1990-2000: Marked Differences Between Groups Defined by Birth Country. Stroke 35: 2054-2058 [Abstract] [Full text]  
  • Britton, A., Shipley, M., Marmot, M., Hemingway, H. (2004). Does access to cardiac investigation and treatment contribute to social and ethnic differences in coronary heart disease? Whitehall II prospective cohort study. BMJ 329: 318- [Abstract] [Full text]  
  • Harding, S. (2004). Mortality of migrants from the Caribbean to England and Wales: effect of duration of residence. Int J Epidemiol 33: 382-386 [Abstract] [Full text]  
  • Blackledge, H. M, Newton, J., Squire, I. B (2003). Prognosis for South Asian and white patients newly admitted to hospital with heart failure in the United Kingdom: historical cohort study. BMJ 327: 526-531 [Abstract] [Full text]  
  • Cappuccio, F. P, Barbato, A., Kerry, S. M (2003). Hypertension, diabetes and cardiovascular risk in ethnic minorities in the UK. British Journal of Diabetes & Vascular Disease 3: 286-293 [Abstract]  
  • Quirke, T P, Gill, P S, Mant, J W, Allan, T F (2003). The applicability of the Framingham coronary heart disease prediction function to black and minority ethnic groups in the UK. Heart 89: 785-786 [Full text]  
  • Chaturvedi, N. (2003). ETHNIC DIFFERENCES IN CARDIOVASCULAR DISEASE. Heart 89: 681-686 [Full text]  
  • Barakat, K, Wells, Z, Ramdhany, S, Mills, P G, Timmis, A D (2003). Bangladeshi patients present with non-classic features of acute myocardial infarction and are treated less aggressively in east London, UK. Heart 89: 276-279 [Abstract] [Full text]  
  • Nazroo, J. Y. (2003). The Structuring of Ethnic Inequalities in Health: Economic Position, Racial Discrimination, and Racism. AJPH 93: 277-284 [Abstract] [Full text]  
  • Cruickshank, K., Riste, L., Anderson, S. G., Wright, J. S., Dunn, G., Gosling, R. G. (2002). Aortic Pulse-Wave Velocity and Its Relationship to Mortality in Diabetes and Glucose Intolerance: An Integrated Index of Vascular Function?. Circulation 106: 2085-2090 [Abstract] [Full text]  
  • Kain, K., Catto, A. J (2002). Insulin resistance syndrome in South Asians. British Journal of Diabetes & Vascular Disease 2: 398-402 [Abstract]  
  • Kain, K., Blaxill, J. M., Catto, A. J., Grant, P. J., Carter, A. M. (2002). Increased Fibrinogen Levels among South Asians versus Whites in the United Kingdom Are Not Explained by Common Polymorphisms. Am J Epidemiol 156: 174-179 [Abstract] [Full text]  
  • Patel, M. G, Wright, D. J, Gill, P. S, Jerwood, D., Silcock, J., Chrystyn, H. (2002). Prescribing of lipid lowering drugs to South Asian patients: ecological study. BMJ 325: 25-26 [Full text]  
  • Whincup, P. H, Gilg, J. A, Papacosta, O., Seymour, C., Miller, G. J, Alberti, K G M M, Cook, D. G (2002). Early evidence of ethnic differences in cardiovascular risk: cross sectional comparison of British South Asian and white children. BMJ 324: 635-635 [Abstract] [Full text]  
  • Feder, G., Crook, A. M, Magee, P., Banerjee, S., Timmis, A. D, Hemingway, H. (2002). Ethnic differences in invasive management of coronary disease: prospective cohort study of patients undergoing angiography. BMJ 324: 511-516 [Abstract] [Full text]  
  • Leggetter, S., Chaturvedi, N., Fuller, J. H., Edmonds, M. E. (2002). Ethnicity and Risk of Diabetes-Related Lower Extremity Amputation: A Population-Based, Case-Control Study of African Caribbeans and Europeans in the United Kingdom. Arch Intern Med 162: 73-78 [Abstract] [Full text]  
  • Raji, A., Seely, E. W., Arky, R. A., Simonson, D. C. (2001). Body Fat Distribution and Insulin Resistance in Healthy Asian Indians and Caucasians. J. Clin. Endocrinol. Metab. 86: 5366-5371 [Abstract] [Full text]  
  • Chaturvedi, N. (2001). Ethnicity as an epidemiological determinant--crudely racist or crucially important?. Int J Epidemiol 30: 925-927 [Full text]  
  • Fischbacher, C. M, Bhopal, R., Unwin, N., White, M., Alberti, K. (2001). The performance of the Rose angina questionnaire in South Asian and European origin populations: a comparative study in Newcastle, UK. Int J Epidemiol 30: 1009-1016 [Abstract] [Full text]  
  • LIVINGSTON, G., LEAVEY, G., KITCHEN, G., MANELA, M., SEMBHI, S., KATONA, C. (2001). Mental health of migrant elders -- the Islington study. Br. J. Psychiatry 179: 361-366 [Abstract] [Full text]  
  • Cruickshank, J. K., Heald, A. H., Anderson, S., Cade, J. E., Sampayo, J., Riste, L. K., Greenhalgh, A., Taylor, W., Fraser, W., White, A., Gibson, J. M. (2001). Epidemiology of the Insulin-like Growth Factor System in Three Ethnic Groups. Am J Epidemiol 154: 504-513 [Abstract] [Full text]  
  • Chaturvedi, N, McKeigue, P M, Marmot, M G, Nihoyannopoulos, P (2001). A comparison of left ventricular abnormalities associated with glucose intolerance in African Caribbeans and Europeans in the UK. Heart 85: 643-648 [Abstract] [Full text]  
  • Kain, K., Catto, A. J., Young, J., Bamford, J., Bavington, J., Grant, P. J. (2001). Insulin Resistance and Elevated Levels of Tissue Plasminogen Activator in First-Degree Relatives of South Asian Patients With Ischemic Cerebrovascular Disease. Stroke 32: 1069-1073 [Abstract] [Full text]  
  • BHOPAL, R., SENGUPTA-WIEBE, S. (2000). Cardiovascular risks and outcomes: ethnic variations in hypertensive patients. Heart 83: 495-496 [Full text]  
  • Maiden, N, Capell, H A, Madhok, R, Hampson, R, Thomson, E A (1999). Does social disadvantage contribute to the excess mortality in rheumatoid arthritis patients?. Ann Rheum Dis 58: 525-529 [Abstract] [Full text]  
  • Banerji, M. A., Faridi, N., Atluri, R., Chaiken, R. L., Lebovitz, H. E. (1999). Body Composition, Visceral Fat, Leptin, and Insulin Resistance in Asian Indian Men. J. Clin. Endocrinol. Metab. 84: 137-144 [Abstract] [Full text]  



Access jobs at BMJ Careers
Whats new online at Student 

BMJ