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a Academic Department of General Practice St Bartholomew's and the London Hospital Medical School Queen Mary and Westfield College London E1 4NS
There is growing consensus that treatment of cardiovascular risks should be based on
multiple rather than single factors and on absolute rather than relative risks. Thresholds for
treatment should reflect the level of absolute risk at which the benefits and hazards of treating
outweigh the benefits and hazards of not treating. Once a decision has been made to initiate a
treatment programme, clinicians need to know the patient's absolute risk. At this level
of risk, do the benefits of treatment outweigh the hazards? Given this information, which
treatment option does the patient prefer? Using cardiovascular disease as an example, I review
some measures that assist decision making in primary care. Practice guidelines should routinely
include accessible presentation of treatment outcomes on benefit, hazard, and costs for a range
of absolute risks. These measures enable patients and their doctors to weigh the pros and cons
of treatment in their particular circumstances.
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