BMJ 1994;308:939-941 (9 April)

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Milk consumption and bone mineral density in middle aged and elderly women

S Murphy, K-T Khaw, H May, J E Compston 

Clinical Gerontology Unit, Addenbrooke's Hospital, Cambridge CB2 2QQ Department of Medicine, Addenbrooke's Hospital, Cambridge CB2 2QQ Correspondence to: Sean Murphy, Department of Clinical Geratology, Radcliffe Infirmary, Oxford OX2 6HE.

Abstract

Objectives : To study the effects of historical milk consumption on current bone mineral density at the hip and spine.
Design : Cross sectional study.
Subjects : 284 community based women aged 44-74 years recruited from four general practice age-sex registers in Cambridge. Subjects categorised their average milk consumption up to age 25, from age 25-44, and from age 44 to the present time as >=1 glass/day, <1 galss/day but >1 glass/week, or <1 glass/week.
Main outcome measures : Bone mineral density at the hip and spine measured by dual energy x ray absorptiometry. Results - Data on milk consumption up to age 25 years were available for 252 women. There was a consistent upward trend in bone mineral density at all sites with increasing historical milk consumption (total hip, femoral neck, trochanter, intertrochanter, P<0.05; Ward's triangle, P=0.005). Adjustment for age and body size did not alter these trends. Milk consumption up to age 25 was a significant independent predictor of bone mineral density at all sites in multiple linear regression analyses controlling for age, body mass index, menopausal status, smoking, ever use of hormone replacement therapy or oral contraceptives, physical activity, and alcohol intake. The effects of milk consumption from age 25-44 and from age 44 to the present were similar in direction though not statistically significant.
Conclusion : Frequent milk consumption before age 25 favourably influences hip bone mass in middle aged and older women.

Public health implications

  • Public health implications

  • Osteoporosis and fractures are an increasing public health problem

  • Bone mineral density is an important predictor of future fracture risk

  • Identification of factors which influence peak bone mass may facilitate the development of preventive strategies

  • In this study frequent milk consumption before age 25 years was associated with higher hip bone mineral density in middle aged and elderly women

  • Milk consumption should be encouraged during childhood and adolescence and may help prevent osteoporotic fractures in later life


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