Br Med J (Clin Res Ed) 1986;293:800-804 (27 September), doi:10.1136/bmj.293.6550.800
Computer aided diagnosis of acute abdominal pain: a multicentre study.
I D Adams,
M Chan,
P C Clifford,
W M Cooke,
V Dallos,
F T de Dombal,
M H Edwards,
D M Hancock,
D J Hewett,
N McIntyre
A multicentre study of computer aided diagnosis for patients
with acute abdominal pain was performed in eight centres with
over 250 participating doctors and 16,737 patients. Performance
in diagnosis and decision making was compared over two periods:
a test period (when a small computer system was provided to
aid diagnosis) and a baseline period (before the system was
installed). The two periods were well matched for type of case
and rate of accrual. The system proved reliable and was used
in 75.1% of possible cases. User reaction was broadly favourable.
During the test period improvements were noted in diagnosis,
decision making, and patient outcome. Initial diagnostic accuracy
rose from 45.6% to 65.3%. The negative laparotomy rate fell
by almost half, as did the perforation rate among patients with
appendicitis (from 23.7% to 11.5%). The bad management error
rate fell from 0.9% to 0.2%, and the observed mortality fell
by 22.0%. The savings made were estimated as amounting to 278
laparotomies and 8,516 bed nights during the trial period--equivalent
throughout the National Health Service to annual savings in
resources worth over 20m pounds and direct cost savings of over
5m pounds. Computer aided diagnosis is a useful system for improving
diagnosis and encouraging better clinical practice.

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