Br Med J 1980;281:481-482 (16 August), doi:10.1136/bmj.281.6238.481
Comparison of nicotine chewing-gum and psychological treatments for dependent smokers.
M Raw,
M J Jarvis,
C Feyerabend,
M A Russell
The results of using nicotine chewing-gum to treat dependent
smokers attending a withdrawal clinic were compared with the
results of psychological treatment. At one-year follow-up 26
(38%) out of 69 people who received nicotine gum were abstinent
compared with seven (14%) out of 49 who received psychological
treatment (p < 0.01). Abstinence was confirmed by the measurement
of carboxyhaemoglobin concentrations or expired air carbon monoxide.
Blood nicotine concentrations when patients used the gum averaged
half the smoking values, and side effects were few. Addiction
occurred in only two subjects. Thus nicotine chewing-gum is
a useful aid to giving up smoking and is probably acceptable
even for people with cardiovascular disease.

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