Table 1 Level of smoking in spouse and deaths from selected causes among male never
smokers in California cancer prevention study (CPS I) cohort, as of 1959 and
1972. Relative risk (95% confidence interval) comparing individuals with each
level of exposure to those without exposure. Proportional hazards linear
models adjusted for age and for age and seven confounders. For reference,
1960-98 death rate in deaths per 1000 person years adjusted to 1960 US
population for attained ages 35-84 is
given18
|
|
All 1959 participants, followed 1960-98
|
1959 participants aged  50, followed 1960-98
|
Participants defined in 1972, followed 1973-98
|
Smoking in spouse and cause of death
|
No of deaths/No of participants
|
Age adjusted relative risk (95% Cl)
|
Fully adjusted relative risk (95% Cl)
|
No of deaths/No of participants
|
Age adjusted relative risk (95% Cl)
|
No of deaths/No of participants
|
Age adjusted relative risk (95% Cl)
|
Coronary heart disease (death rate 3.05/1000)
|
|
|
|
|
|
|
Never (1)*
|
1860/7458
|
1.00
|
1.00
|
1534/5201
|
1.00
|
806/3404
|
1.00
|
Former (2)*
|
126/624
|
0.94 (0.78 to 1.12)
|
0.94 (0.77 to 1.14)
|
83/323
|
0.93 (0.74 to 1.16)
|
114/573
|
0.94 (0.77 to 1.14)
|
Current (cigarettes/day):
|
|
|
|
|
|
|
|
1-9 (3)*
|
81/392
|
0.97 (0.78 to 1.21)
|
0.98 (0.78 to 1.24)
|
59/230
|
1.00 (0.77 to 1.30)
|
20/89
|
1.32 (0.84 to 2.06)
|
10-19 (4)*
|
99/513
|
0.86 (0.70 to 1.05)
|
0.82 (0.66 to 1.02)
|
73/282
|
0.91 (0.72 to 1.15)
|
33/153
|
1.02 (0.72 to 1.45)
|
20 (5)*
|
81/458
|
0.92 (0.74 to 1.15)
|
0.89 (0.70 to 1.13)
|
58/245
|
1.02 (0.78 to 1.32)
|
35/189
|
0.94 (0.67 to 1.32)
|
21-39 (6)*
|
27/129
|
1.16 (0.79 to 1.69)
|
1.13 (0.76 to 1.68)
|
19/62
|
1.30 (0.82 to 2.04)
|
14/58
|
1.20 (0.70 to 2.03)
|
40 (7)*
|
13/45
|
1.29 (0.75 to 2.22)
|
1.24 (0.70 to 2.19)
|
9/26
|
1.25 (0.65 to 2.41)
|
4/36
|
0.65 (0.24 to 1.73)
|
Total of current smokers
|
301/1537
|
0.94 (0.83 to 1.07)
|
0.92 (0.80 to 1.05)
|
218/845
|
1.00 (0.87 to 1.15)
|
106/525
|
1.04 (0.85 to 1.27)
|
Ever
|
427/2161
|
0.94 (0.85 to 1.05)
|
0.93 (0.83 to 1.04)
|
301/1168
|
0.98 (0.86 to 1.11)
|
220/1098
|
0.99 (0.85 to 1.15)
|
7 level index
|
2287/9619
|
0.99 (0.95 to 1.02)
|
0.98 (0.94 to 1.02)
|
1835/6369
|
1.00 (0.96 to 1.05)
|
1026/4502
|
1.00 (0.95 to 1.05)
|
Lung cancer (death rate 0.11/1000)
|
|
|
|
|
|
|
Never
|
65
|
1.00
|
1.00
|
50
|
1.00
|
27
|
1.00
|
Former
|
5
|
0.92 (0.37 to 2.30)
|
0.82 (0.29 to 2.26)
|
3
|
0.89 (0.28 to 2.88)
|
3
|
0.63 (0.19 to 2.09)
|
Current
|
9
|
0.69 (0.34 to 1.39)
|
0.57 (0.26 to 1.26)
|
5
|
0.60 (0.24 to 1.52)
|
1
|
0.23 (0.03 to 1.68)
|
Ever
|
14
|
0.75 (0.42 to 1.35)
|
0.63 (0.33 to 1.22)
|
8
|
0.69 (0.32 to 1.46)
|
4
|
0.43 (0.15 to 1.24)
|
7 level index
|
79
|
0.94 (0.77 to 1.14)
|
0.88 (0.70 to 1.10)
|
58
|
0.91 (0.71 to 1.17)
|
31
|
0.68 (0.41 to 1.13)
|
Chronic obstructive pulmonary disease (death rate 0.12/1000)
|
|
|
|
|
|
Never
|
69
|
1.00
|
1.00
|
59
|
1.00
|
30
|
1.00
|
Former
|
5
|
0.95 (0.38 to 2.37)
|
1.00 (0.40 to 2.50)
|
4
|
1.09 (0.40 to 3.02)
|
4
|
0.88 (0.31 to 2.50)
|
Current
|
17
|
1.40 (0.82 to 2.40)
|
1.28 (0.72 to 2.27)
|
13
|
1.51 (0.82 to 2.78)
|
7
|
1.80 (0.78 to 4.17)
|
Ever
|
22
|
1.27 (0.78 to 2.08)
|
1.20 (0.72 to 2.00)
|
17
|
1.39 (0.81 to 2.41)
|
11
|
1.29 (0.64 to 2.61)
|
7 level index
|
91
|
1.06 (0.91 to 1.25)
|
1.05 (0.88 to 1.24)
|
76
|
1.09 (0.91 to 1.30)
|
41
|
1.08 (0.86 to 1.38)
|
|
* Values in parentheses are index level of environmental tobacco smoke.