Predictive factors for adult height gain in
patients with growth hormone deficiency: final
model
Variable*
Regression coefficient (95%
CI)
P value
No of patients in final model
(r2)
1885
(0.58)
Patients' characteristics:
Target height (SD
score)
0.22 (0.19 to 0.25)
<0.0001
Birth weight (SD
score)
0.11 (0.08 to 0.13)
<0.0001
Sex (male=1,
female=0)
0.54 (0.62 to 0.47)
<0.0001
Baseline
variables:
Age (years)
0.31 (0.28 to 0.33)
<0.0001
Pubertal (yes=1, no=0)
0.19 (0.26 to
0.11)
<0.0001
Bone age delay (years)
0.18 (0.15 to
0.20)
<0.0001
Weight (SD score)
0.19 (0.23 to
0.14)
<0.0001
Log peak growth hormone concentration
(µg/l)
0.08 (0.13 to 0.03)
0.002
Treatment
variables:
Completion of treatment as scheduled (yes=1,
no=0)
0.30 (0.37 to 0.22)
<0.0001
Duration of
treatment (years)
0.22 (0.19 to 0.25)
<0.0001
SD=standard deviation.
*
The model includes baseline height SD score, time interval
between baseline and adult height measurements, and the interaction
between these two variables; therefore, the model similarly predicts
the factors for adult height itself (in SD).
The regression coefficient represents the change in SD score
per unit change in predictor.
The number of subjects corresponds to those with no missing
value for any predictor variable.