|
Table 3 Numbers (percentages) of
subjects who were seroprotected at two and six months after vaccination (intention to treat
analysis)
|
|
|
|
Month |
| Antigen
(µg) |
No of subjects |
2 |
6 |
|
| 5 |
25 |
5 (20) |
1 (4) |
| 10 |
25 |
3 (12) |
6 (24) |
| 20 |
25 |
8 (32) |
10 (40) |
| 40 |
25 |
11 (44) |
9 (36) |
| Total |
100 |
27 (27) |
26 (26) |
| Odds ratio for a doubling in dose of vaccine (95%
confidence interval) |
|
1.63 (1.07 to 2.49) |
1.87 (1.20 to 2.92) |
| P value |
|
0.02 |
0.006 |
|