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BMJ No 7124 Volume 316

Minerva Saturday 3 January 1998




photo - scarred breast


After a mastectomy women should be offered the whole range of reconstructive options. One of these is the transfer of skin and muscle from the abdominal wall to the chest with microvascular techniques. Patients should be warned that with this method the sensation of the reconstructed breast will not be normal. This woman aged 58 burnt her reconstructed breast on a hot water bottle. Otherwise she was delighted by the success of the procedure.

Alastair J Platt, specialist registrar in plastic surgery,
Ivan T H Foo, consultant plastic surgeon,
Bradford Royal Infirmary, Bradford BD9 6RJ

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Americans continue to dispute the value of mammography in women aged 40-49. An analysis in Annals of Internal Medicine (1997;127:955-65) has concluded that "screening is relatively cost ineffective in women aged 40-49.... To prevent one death clinicians would need to screen 2500 women, whereas routine screening of only 270 women aged 50-69 would also prevent one death."

Hereditary haemochromatosis is a disorder of iron metabolism that affects 1 in 300 people of Northern European descent: the carrier rate is about 10%, and a simple genetic test will identify 90% of the homozygotes (Gut 1997;41:841-4). The disease may be fatal if not treated, but if treatment is started early in life the life expectancy is normal. A chill note in the report warns that before genetic testing is introduced "ethical issues need to be addressed such as how insurance companies will view homozygous people with no signs of iron overload."

Minerva is a long term fan of the British Kidney Patient Association, which since 1975 has raised funds to improve the quality of lives of patients who have developed renal failure. Its appeal includes an article by Sir Cyril Chantler recalling that when he started recommending transplants for children he was worried about the length of time the grafts would survive. Ten year patient survival rates now average 88% for children over the age of 5, and many of the pioneer patients have children of their own (BKPA, Bordon, Hampshire GU35 9JZ).

A study in Australia of the sexual behaviour of homosexual men found that those who were HIV positive were more likely than the others to have unprotected anal sex (AIDS Care 1997;9:637-49). The explanation is that the HIV positive men sought out positive partners for unprotected sex - but as the report points out, apart from a risk of reinfection with different strains of HIV and other infection, there is a possibility of (re)infection with drug resistant strains of HIV.

Doctors and members of the public who argue that patients with alcoholic liver disease should be given lower priority for liver transplantation than those with more "deserving" diseases have no medical evidence on which to base their prejudice (British Journal of Psychiatry 1997;171:497-500). The short and long term outcomes for patients with alcoholic liver disease are similar to those for patients with other liver diseases, even when the small proportion who return to misusing alcohol is taken into account.

As a student Minerva was taught to give digoxin to all patients in heart failure. Later she learnt that it was useful only in patients with atrial fibrillation. But the results of studies reviewed in the European Heart Journal (1997;18:1685-8) have shown that patients in sinus rhythm do benefit from digoxin and that the benefit continues for years. Angiotensin converting enzyme inhibitors and digoxin remain the treatments of proved value for most patients with severe heart failure.

Patients with pain in the chest who have a raised ST segment in their electrocardiogram have clearly sustained an infarct; but what about those without this sign? A study of 773 patients seen in an emergency room in Hamburg (New England Journal of Medicine 1997;337:1648-53) found that measurement of the serum concentrations of troponin I and T distinguished between patients with myocardial damage and those without in 99% of cases. The report concludes that a negative result of this test allows rapid, safe discharge of patients who have come to hospital complaining of chest pain.

The picture paragraph showing the telephone bill of a woman with dementia (1997;315:1478) omitted the name of one of the authors, Dr E Davies, senior house officer in psychiatry. This was an oversight by Minerva, who offers her apologies.

Two thirds of doctors and nurses working in an accident and emergency department in London were not in favour of relatives being present in the resuscitation room (Journal of Accident and Emergency Medicine 1997;14:366-9). The more experienced that staff were, however, the more likely they were to agree that relatives might benefit from being present, and the report concludes that training for emergency room staff should include the management of distressed relatives observing a resuscitation.

A survey by the audit unit of the Royal College of Obstetricians and Gynaecologists of endometrial destruction procedures collected data from 690 doctors who had treated 10,680 women (British Journal of Obstetrics and Gynaecology 1997;104:1329-31). The main finding was a complication rate of 4.45, showing that any form of ablation or resection was safer than a hysterectomy. Ablation by laser or roller ball proved safer than the procedure with a resectoscope.

Studies in sleep laboratories suggest that young adults should sleep for 8-9 hours each night. A survey of 1,007 young Americans (American Journal of Public Health 1997;87:1649-53) found that they had been averaging fewer than seven hours and that many were bothered by daytime sleepiness. Sleepiness was most prevalent in single people who worked full time - who should, presumably, either work less or play less.

Cirrhosis of the liver is perceived as a chronic disease, but some data from Sweden (Addiction 1997;92:1523-36) showed that a fall of 1 litre of alcohol per year in average consumption in Stockholm was associated with a fall of 12% in mortality from cirrhosis in the same year.

Pregnant women develop cholecystitis no more or less frequently than those who are not pregnant, but they present greater problems. A review in the British Journal of Surgery (1997;84:1646-50) concludes that surgery should be avoided if possible since cholecystectomy is associated with a high rate of fetal loss. In fact, over 90% of patients do well when treated conservatively. Laparoscopic surgery may have changed the picture: 60 cases have been reported with no perinatal or maternal mortality, and the operation can be done under epidural anaesthesia.


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